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The objective of this study is to evaluate the efficacy of intravenous micafungin for the empirical antifungal therapy, pre-emptive antifungal therapy, diagnostic driven antifungal therapy or targeted antifungal therapy patients with invasive fungal infections caused by Candida sp. or Aspergillus sp. (fungemia, respiratory mycosis, gastrointestinal mycosis) in adult patients in China.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Micafungin group |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Micafungin | Drug | Intravenous |
|
| Measure | Description | Time Frame |
|---|---|---|
| Overall success rate | Overall success rate=number of overall success patients/number of patients for efficacy evaluation × 100% | Up to 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Overall incidence and severity of adverse events | Up to 12 months | |
| Overall incidence and severity of adverse drug reactions | Up to 12 months |
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Inclusion Criteria:
Exclusion Criteria:
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The hospitalized patients who received intravenous micafungin for treatment according to the clinical judgment of the treating physician before the end of April 2015
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| Name | Affiliation | Role |
|---|---|---|
| Medical Director | Astellas Pharma China, Inc. | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Beijing | China | |||||
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30105657 | Derived | Zheng X, Huang X, Luo J, Li J, Li W, Liu Q, Niu T, Wang X, Zhou J, Zhang X, Hu J, Liu K. Effectiveness and Tolerability of Micafungin in Chinese Patients with Invasive Fungal Infections: A Retrospective, Multicenter Study. Adv Ther. 2018 Sep;35(9):1400-1410. doi: 10.1007/s12325-018-0762-5. Epub 2018 Aug 13. |
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| Changchun |
| China |
| Chengdu | China |
| Chongqing | China |
| Fuzhou | China |
| Guangzhou | China |
| Guizhou | China |
| Haikou | China |
| Hangzhou | China |
| Harbin | China |
| Hengyang | China |
| Langfang | China |
| Shanghai | China |
| Shijiazhuang | China |
| Wuhan | China |
| Xiamen | China |
| Zhengzhou | China |
| ID | Term |
|---|---|
| D000072742 | Invasive Fungal Infections |
| C536972 | Torulopsis |
| D001228 | Aspergillosis |
| ID | Term |
|---|---|
| D009181 | Mycoses |
| D001423 | Bacterial Infections and Mycoses |
| D007239 | Infections |
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| ID | Term |
|---|---|
| D000077551 | Micafungin |
| ID | Term |
|---|---|
| D055666 | Lipopeptides |
| D008055 | Lipids |
| D010455 | Peptides |
| D000602 | Amino Acids, Peptides, and Proteins |
| D054714 | Echinocandins |
| D010456 | Peptides, Cyclic |
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