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Fifty pregnant patients with acquired and congenital heart disease between 38-41 weeks were randomised into elective induction and spontaneous labour groups only after bishop score was equal to or more than 6.It was concluded that induction of labour with oxytocin is a relatively safe procedure in women with low risk heart disease with NYHA class I and II. It resulted in a similar caesarean delivery rate and was not associated with more maternal and neonatal complications.
Induction of labour was done with oxytocin. An infusion of 30U oxytocin diluted in 500ml normal saline was prepared and given through infusion pump at initial rate of 3mU/min. Subsequently dose was increased 3mU/min every 45 min till adequate uterine contractions were established.
Epidural analgesia was provided wherever feasible or Injection Morphine 2-5mg was given intravenously for pain relief.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| induction of labour | Active Comparator | drug- infusion of 30U oxytocin diluted in 500ml normal saline given at rate of 3mU/min and subsequently dose increased 3mU/min every 45 min |
|
| Spontaneous Labour | No Intervention | patients were allowed to go into spontaneous labour |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Oxytocin | Drug | Arm - Induction of labour |
|
| Measure | Description | Time Frame |
|---|---|---|
| Duration of labour | at the time of delivery | |
| Rate of caesarean section | mode of delivery and rate of caesarean section with indication | at the time of delivery |
| Number of patients with delivery during workday hours | at the time of delivery |
| Measure | Description | Time Frame |
|---|---|---|
| number of patients with maternal complications | maternal complications include postpartum hemorrhage, infection, cardiac complications and number of maternal deaths | day 5 |
| number of patients with adverse neonatal outcome |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Post Graduate Institute of Medical Education and Research | Chandigarh | Chandigarh | 160012 | India |
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| ID | Term |
|---|---|
| D004194 | Disease |
| D011248 | Pregnancy Complications |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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| ID | Term |
|---|---|
| D010121 | Oxytocin |
| ID | Term |
|---|---|
| D010909 | Pituitary Hormones, Posterior |
| D010907 | Pituitary Hormones |
| D036361 | Peptide Hormones |
| D006728 | Hormones |
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apgar score number of admissions to neonatal intensive care unit number of neonatal deaths
| day 5 |
| D006730 |
| Hormones, Hormone Substitutes, and Hormone Antagonists |
| D010455 | Peptides |
| D000602 | Amino Acids, Peptides, and Proteins |