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Current research aimed to compare the efficacy of computer-assisted cognitive rehabilitation (CACR), stimulant drugs and Placebo CACR on executive functions and clinical symptoms of children with attention deficit/hyperactivity disorder (ADHD).
The investigators administered a randomized controlled trial (RCT) through random assignment of ADHD subjects in to three different groups to compare the effects of CACR, immediate-release methylphenidate, and a Placebo CACR (i.e. some computerized tasks assumed not having any therapeutic effects) on the functioning of children with ADHD.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Computerized cognitive rehabilitation | Experimental | -Computer-assisted cognitive rehabilitation (CACR): 20 Ninety-minute sessions of CACR. |
|
| Placebo CACR [PCACR] | Placebo Comparator | -PCACR group simultaneously received 20 Ninety-minute sessions of Placebo CACR. |
|
| Ritalin | Experimental | -2 to 3 doses of 10 mg Ritalin tablets per day during two months. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Computerized cognitive rehabilitation | Other | - Computerized cognitive rehabilitation: 20 ninety-minute sessions of computerized cognitive rehabilitation. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Persian software for the continuous performance test [CPT] | The Persian software of CPT is a visual CPT test. | 5 months |
| Persian software for the Tower of London Test [TOL] | Persian TOL is a software version of tower of London test (TOL) which was developed in Iran. | 5 months |
| Forward/Reversed digit span tasks from the WISC-R testing battery. | Reversed digit span from the WISC-R (Wechsler, 1974) was used to measure executive verbal WM and the forward digit span was used to measure short-term memory. | 5 months |
| Raven's colored progressive matrices. | Raven's colored progressive matrices (Raven, 1995) was used to measure complex non-verbal reasoning. | 5 months |
| Span board task from the Lumosity.com online software (Lumosity.com, 2012) | 5 months | |
| SNAP-IV scales | 5 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Saeed Azami, MSc | Candidate for PhD in Psychology, Department of Psychology, Semnan University, Semnan, Iran | Principal Investigator |
| Alireza Moghadas, PhD | Department of Clinical Psychology, Allameh Tabatabaei University, Tehran, Iran. | Study Director |
| Faramarz Sohrabi, PhD | Department of Clinical Psychology, Allameh Tabatabaei University, Tehran, Iran. | Study Director |
| Morteza Nazifi, PhD | Department of psychology, University of Bojnord, Bojnord, Iran. | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Counseling and guidence Center of the Department of education of region 9 of Tehran | Tehran | Tehran Province | Iran |
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| Ritalin | Drug | -drug therapy: 2 or 3 doses of 10 mg tablets of Immediate-release Methylphenidate (Ritalin) per day for 2 months. |
|
|
| Placebo CACR [PCACR] | Other | PCACR: 20 ninety-minute sessions of Placebo computerized cognitive training. |
|
| ID | Term |
|---|---|
| D001289 | Attention Deficit Disorder with Hyperactivity |
| ID | Term |
|---|---|
| D019958 | Attention Deficit and Disruptive Behavior Disorders |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| D008774 | Methylphenidate |
| ID | Term |
|---|---|
| D010648 | Phenylacetates |
| D000146 | Acids, Carbocyclic |
| D002264 | Carboxylic Acids |
| D009930 | Organic Chemicals |
| D010880 | Piperidines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
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