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| Name | Class |
|---|---|
| St. Olavs Hospital | OTHER |
| SINTEF Health Research | OTHER |
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This is a substudy of "Generation 100". The investigators will follow the persons with atrial fibrillation to see if 3 years of interval or moderate exercise affects the burden of atrial fibrillation, symptoms, use of health services or echocardiographic findings.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Moderate exercise | Experimental | Moderate exercise |
|
| Control | Experimental | Control group |
|
| Interval exercise | Experimental | interval exercise |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Interval exercise | Behavioral | 4 times of 4 minutes intervals at an intensity of 90-95% of maximum heart rate and active pauses of 3 minutes between intervals. 3 times a week for 3 years. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in burden of atrial fibrillation | Burden of atrial fibrillation; measured by Holter monitor and the patient. | At baseline and 3 years |
| Measure | Description | Time Frame |
|---|---|---|
| Size of left ventricle | Echocardiographic measures | At baseline and 3 years |
| Quality of life | Measured with SF-36 | At baseline and 3 years |
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Inclusion Criteria:
Exclusion Criteria:
-
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| Name | Affiliation | Role |
|---|---|---|
| Jan Paal Loennechen, PhD | St. Olavs Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Norwegian University of Science and Technology | Trondheim | 7491 | Norway |
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| ID | Term |
|---|---|
| D001281 | Atrial Fibrillation |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D001145 | Arrhythmias, Cardiac |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D010335 | Pathologic Processes |
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| Moderate exercise | Behavioral | Moderate exercise with pulse about 70% of max pulse; 3 times a week for 3 years. |
|
| Control | Behavioral | Given information on recommendations for physical activity. |
|
| Endothelial function | Diameter of brachial artery measured by ultrasound. | At baseline and 3 years |
| Maximal oxygen uptake | At baseline and 3 years |
| Atrial extrasystoles | Measured with Holter monitor | At baseline and 3 years |
| Number of hospitalisations with atrial fibrillation as main diagnosis | Total number during the 3 year intervention period |
| Total number of electrical cardioversions | Number of electrical cardioversions because og atrial fibrillation | During the 3 years of intervention |
| Change in burden of atrial fibrillation | Measured by Holter and the patient. | Baseline and 1 year |
| Size of left atrium | Echocardiography | Baseline and 1 year |
| Function of left atrium | Echocardiographic measures | At baseline and 3 years |
| Function of left ventricle | Echocardiographic measures | At baseline and 3 years |
| Size of left atrium | Echocardiographic measures | At baseline and 3 years |
| Symptom burden | Measured with Symptom and Severity Checklist. | At baseline and 3 years |
| D013568 |
| Pathological Conditions, Signs and Symptoms |
| D001519 | Behavior |