The purpose of this 8-week intervention trial is to investigate the effect of a dietary supplement (containing citrus bioflavonoids and vitamin E) plus fish oil supplementation in healthy hyperlipidemic subjects

Inclusion Criteria:

• men and women ≥ 18 and ≤ 72 years old
• generally healthy
• BMI > 18 and < 38
• LDL cholesterol ≥ 130 mg/dl and < 270 mg/dl
• triglycerides ≥ 150 mg/dl and < 400 mg/dl
• ability to understand and the willingness to sign a written informed consent

Exclusion Criteria:

• use of nutritional supplements and medical foods for dyslipidemia within 30 days prior to the study
• use of omega-3 fatty acid dietary supplements within 30 days prior to the study
• use of prescription HMG-CoA reductase inhibitors, bile acid sequestrants, fibrates, cholesterol absorption blocking agents, or niacin
• use of prescription medications and/or nonprescription medications for acute and semi-acute medical conditions
• history of cardiovascular disease, type i diabetes, autoimmune disease, liver or kidney disease, malignancy, and serious mental illness.
• known infection with HIB, TB, hepatitis B or hepatitis C
• history of allergy or intolerance to study products
• smoking, use of nicotine-containing products, or use of drugs of abuse 30 days prior to the study
• history of regular intake of > 14 alcoholic drinks per week for females and > 21 drinks per week for males