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| ID | Type | Description | Link |
|---|---|---|---|
| #2232 | Other Identifier | The University of memphis |
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| Name | Class |
|---|---|
| Nordic Naturals | INDUSTRY |
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The purpose of this study to determine whether Fish oil (Omega-3 Fatty Acid) supplementation has an impact on inflammation and lean body mass in older adults. The investigators expect that Fish oil supplementation will reduce inflammation and prevent the loss of lean mass compared to placebo.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Fish oil (Omega-3 fatty acid) | Experimental | 2 capsules/day of ProOmega providing 650mg EPA and 450mg DHA |
|
| Soybean oil | Placebo Comparator | 2 capsules/day |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Omega-3 fatty acid | Dietary Supplement | Omega-3 fatty acid, Eicosapentaenoic acid+docosahexaenoic acid in capsule form |
|
| Measure | Description | Time Frame |
|---|---|---|
| C-Reactive protein | Inflammatory marker | At baseline testing and at 3 month endpoint |
| IL6 | Inflammatory cytokine | At baseline and at 3 month endpoint |
| TNFα | Inflammatory cytokine | At baseline and at 3 month endpoint |
| Measure | Description | Time Frame |
|---|---|---|
| Skeletal muscle mass/body composition | The amount of skeletal muscle mass and fat mass and their ration will be determined. | At baseline testing and at 3 month endpoint |
| Lower body muscular strength |
| Measure | Description | Time Frame |
|---|---|---|
| EPA and DHA | To determine the effectiveness of fish oil supplementation, we measure EPA and DHA Omega-3 fatty acid levels | At baseline and at 3 month endpoint |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Zsolt Murlasits, Ph.D. | The University of Memphis | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Health and Sport Sciences, The University of Memphis | Memphis | Tennessee | 38152 | United States |
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| ID | Term |
|---|---|
| D007249 | Inflammation |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D015525 | Fatty Acids, Omega-3 |
| ID | Term |
|---|---|
| D004042 | Dietary Fats, Unsaturated |
| D004041 | Dietary Fats |
| D005223 | Fats |
| D008055 | Lipids |
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| Placebo | Dietary Supplement | Placebo |
|
Measurement of maximum strength in the leg press exercise
| At baseline and at 3 month endpoint |
| Upper body muscular strength | Measurement of maximum strength in the chest press exercise | At baseline and at 3 month endpoint |
| D005231 |
| Fatty Acids, Unsaturated |
| D005227 | Fatty Acids |
| D005395 | Fish Oils |
| D009821 | Oils |