The Association Between Arterial Stiffness and Assessment of Hydration State in Peritoneal Dialysis Patients

Volume Status in Peritoneal Dialysis Patients With Using Different Determining Methods.

Dry weight (DW) assessment is essential for the efficient treatment of peritoneal dialysis (PD) patients but so far objective methods for DW assessment have not been established for daily clinical practice. Our aim was to evaluate hydration state in PD patients by using a body composition monitor (BCM) and calf bioimpedance (c-BI) and N-terminal prohormone of brain natriuretic peptide (NT-proBNP) levels and to compare both methods with arterial stiffness.

We evaluated 60 patients using a new BCM device that implies a validated body composition model. This method allows correct quantification of extracellular fluid overload or deficiency (normal limits:-1.1 to +1.1L). Patients were assigned to normo and hypervolemic groups according to BCM results. Also, normalized calf resistivity (nRho) was calculated from resistance at 5 Khz using c-BI and the levels of NT-proBNP were measured in all study patients. The analyses of arterial stiffness were performed by using the pulse wave velocity (PWV) technique on the patients. All patients underwent conventional echocardiography and their left ventricular diastolic functions were evaluated.

Inclusion Criteria:

• Peritoneal dialysis patients
• All participants over 18 years of age

Exclusion Criteria:

• Patients with valvular heart disease
• Patients with coronary artery disease
• Patients with cardiomyopathy
• Patients with ESRD who underwent hemodialysis