No longer willing to continue clinical trials

The purpose of this study is to investigate the efficacy and safety of autologous transplantation of Adipose Tissue derived Mesenchymal stem cells (MSCs) in patient with lumbar intervertebral disc degeneration.

Inclusion Criteria:

• Subjects who understand and sign the consent form for this study
• Age :19-70, males and females
• Have chronic low back pain for at least 1 year
• Have failed 1 year of non-operative low back pain management
• Have degenerated intervertebral disc on T2-weighted MR images
• confirmed by positive discography
• Have significant lumbar instability at degenerated intervertebral disc

Exclusion Criteria:

• Have significant lumbar herniated intervertebral disc
• Women who are pregnant or breast feeding or planning to become pregnant during the study
• History or current evidence of alcohol or drug abuse or is a recreational user of illicit drugs or prescription medications
• Serious pre-existing medical conditions like Cardiovascular Diseases, Renal Diseases, Liver Diseases, Endocrine Diseases, Cancer and Diabetes Mellitus
• Participation in another clinical trial or treatment with a different investigational product within 30 days prior to inclusion in the study
• Other pathologic conditions or circumstances that difficult participation in the study according to medical criteria