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| ID | Type | Description | Link |
|---|---|---|---|
| P50DA009241 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute on Drug Abuse (NIDA) | NIH |
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The purpose of this study is to investigate whether monetary reinforcement for performance will enhance the effects of cognitive remediation therapy for substance users seeking treatment at an outpatient facility.
Forty individuals seeking treatment for an alcohol or cocaine use disorder at the Substance Abuse Treatment Unit (SATU) will be randomized to receive cognitive remediation therapy with or without additional compensation based on performance. Participants will use the computerized cognitive remediation program (PSSCogRehab 2012) three times per week for four weeks. The primary outcome measure will be an improved performance on the computerized tasks, with secondary outcomes of changes in cognitive functioning (e.g., attention, concentration, memory) as measured by neuropsychological tests between baseline and post-treatment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| CRT-S | Active Comparator | Cognitive Remediation Therapy - Standard |
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| CRT-CM | Experimental | Cognitive Remediation Therapy plus Contingency Management |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cognitive Remediation Therapy - Standard | Behavioral | Computerized cognitive remediation therapy provided three times per week for four weeks |
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| Measure | Description | Time Frame |
|---|---|---|
| Improvement in performance scores on computerized cognitive remediation tasks | Performance scores on various computerized cognitive remediation tasks will be measured repeatedly during the 4 week study. These scores include "time to completion", "number of errors", "number of words correctly recalled", and "percentage of task completed" | 4 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Improved cognitive function on neuropsychological tests | Change in cognitive function between baseline and post-treatment will be measured by performance on neuropsychological tests, such as Trail Making Test A & B, Wisconsin Card Sort Test, Digit Symbol Test from WAIS-IV, and the Continuous Performance Test-II (CPT-II). | 4 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Brian D Kiluk, PhD | Yale University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Substance Abuse Treatment Unit | New Haven | Connecticut | 06511 | United States |
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| ID | Term |
|---|---|
| D019966 | Substance-Related Disorders |
| D001523 | Mental Disorders |
| ID | Term |
|---|---|
| D064419 | Chemically-Induced Disorders |
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| Cognitive Remediation Therapy plus Contingency Management | Behavioral | Standard cognitive remediation therapy plus monetary incentives based on performance provided three times per week for four weeks. |
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