NHANES Urinary Sodium Calibration Study

National Health and Nutrition Examination Survey (NHANES), Urinary Sodium Calibration Study

This proposed calibration study is designed to evaluate the correlation of urinary sodium excretion between NHANES timed urine and 24-hour urine collections.

The study will be conducted with 400 volunteer participants aged 18-39 years old. Participants will be asked to collect urine samples over a 24-hour period. One-third of the participants (n=133) will be asked to collect a second 24-hour urine 4-11 days later. A 24-hour dietary recall interview will be collected after the completion of each 24-hour urine collection. Results from this study will be used to assess how well the sodium excretion estimated from NHANES timed urine correlates with data from 24-hour urine collection. It will provide valuable information on the potential of NHANES timed urine collections to be used to characterize trends in U.S. population sodium intake.

Inclusion Criteria:

English speaking

• Aged 18-39 years old
• 50% Black; 50% all other
• 50% male; 50% female
• At least 50 (25 male; 25 female) of the 400 participants likely to have high sodium diet indicated by selected dietary behaviors
• At least 50 (25 male; 25 female) of the 400 participants likely to have low sodium diet indicated by selected dietary behaviors

Exclusion Criteria:

• Pregnant or trying to get pregnant.
• Taking loop diuretics
• Chronic kidney disease
• New hypertension treatment or change in hypertension treatment in the last 2 weeks