Effect of Acute Treatment With N2O on Inhibitory Pain Mechanisms in Healthy Subject
Effect of Acute Treatment With N2O on Inhibitory Pain Mechanisms in Healthy Subject
The purpose of this study is to determine whether N2O (laughing gas) has an antinociceptive effects in healthy volunteers.
10 healthy volunteers will come twice to the pain medicine unit, at 1 visit they'll get N2O and in the second visit they'll get air as placebo, they won't know what they're getting. During the visit they'll get heat stimulus using QST and will have to report their pain using eVAS (scale from 0 to 100 when 0 is no pain and 100 is the worst pain imagine).
Inclusion Criteria:
Exclusion Criteria:
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