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This study evaluates the effects of different therapies in ovulation induction in Intrauterine Insemination Cycles.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| HP-hMG | Active Comparator |
| |
| rFSH plus rLH | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Meropur 150 a day | Drug | one subcutaneous injection a day |
| |
| Gonal-f 150 plus Luveris 150 |
| Measure | Description | Time Frame |
|---|---|---|
| ongoing pregnancy rate | 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| number of cancelled cycles for low or no response, the number of interrupted cycles for high risk of OHSS and multiple pregnancies | 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| duration of stimulation, total gonadotropin dose, number of midsize follicles, dominant follicles, E2 levels, endometrial thickness on hCG day, Progesterone levels, endometrial thickness on the midluteal phase. | 30 days |
Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Policlinico Agostino Gemelli | Rome | Rome | 00168 | Italy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25398971 | Derived | Moro F, Scarinci E, Palla C, Romani F, Familiari A, Tropea A, Leoncini E, Lanzone A, Apa R. Highly purified hMG versus recombinant FSH plus recombinant LH in intrauterine insemination cycles in women >/=35 years: a RCT. Hum Reprod. 2015 Jan;30(1):179-85. doi: 10.1093/humrep/deu302. Epub 2014 Nov 14. |
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| Drug |
one subcutaneous injection a day |
|
| ID | Term |
|---|---|
| D007247 | Infertility, Female |
| ID | Term |
|---|---|
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D000091662 | Genital Diseases |
| D007246 | Infertility |
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