Effect of Caloric Restriction and Gastric Bypass on Resting Metabolic Rate

Effect of Caloric Restriction and Gastric Bypass on Resting Metabolic Rate in Obese Subjects

Studies in overweight and obese subjects show a decline in resting metabolic rate (RMR) even after moderate caloric restriction. Yet the onset and course of such a metabolic adaption is still unclear. Lower resting metabolic rates were also reported after gastric banding bariatric surgery but have not yet been investigated in subjects after gastric bypass. The purpose of this study is to investigate the consequences on resting metabolic rate in subjects with obesity after moderate caloric restriction or gastric bypass.

Inclusion Criteria:

• BMI ≥30 kg/m2

Exclusion Criteria:

• Marked weight reduction in the last 2 years (>5% of initial body weight)
• Recent extreme fasting (during the last month)
• Manifest eating disorders (assignment to a specialist for eating disorders)
• Severe psychiatric disorders requiring treatment
• Pregnancy, lactation