A Pilot Study to Evaluate the Effect of Pomegranate Juice on Semen Parameters in Healthy Male Volunteers

A Pilot Study to Evaluate the Effect of Pomegranate Juice on Semen Parameters in Healthy Male Volunteers

How daily consumption of pomegranate juice affects the concentration, morphology or motility of sperm in healthy men.

To determine, in this pilot study, whether daily consumption of pomegranate juice (POM) affects the concentration, morphology or motility of sperm in healthy men. The purpose of the present pilot study is to examine the hypothesis that POM may improve semen parameters in men.

Inclusion Criteria:

• 12 healthy men aged 18-40
• normal sperm counts

Exclusion Criteria:

• History of undescended testes or surgery to the scrotal contents,
• History of marijuana or alcohol abuse, hot tub usage at least 3 months prior to entry into the study
• No alpha adrenergic medications within two weeks of entry into the study,
• No anabolic steroid use,
• No anticholinergic or antimuscarinic drugs, use of colchicine, cimetidine, sulfasalazine, antipsychotics, antidepressants, immunosuppressive drugs prior use of any chemotherapeutic drugs, or UTI on screening visit.