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| Name | Class |
|---|---|
| Videns- og Forskningscenter for Alternativ Behandling | OTHER |
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this is a prospective randomized placebo-controlled double-blinded trial investigating the effect of plant extracts from Alpinia galanga and Punica granatum on human semen quality. The investigators hypothesize that these plant extracts will improve semen quality.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Plant extracts | Active Comparator |
| |
| Placebo | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Extracts of Punica granatum and Alpinia galanga | Dietary Supplement | Tablets, two in the morning and two in the evening |
|
| Measure | Description | Time Frame |
|---|---|---|
| Count of motile sperm per ejaculate | Each participant is given plant extract for three months with flanking semen analyses. |
| Measure | Description | Time Frame |
|---|---|---|
| Morphology: percentage of morphologically abnormal sperm in the ejaculate | If we find an increase in the primary outcome measure in data from participants receiving plant extracts and not in those receiving placebo tablets, we wish to further investigate whether sperm morphology also improves when consuming the plant extracts, e.g. whether the percentage of abnormal sperm in an ejaculate decreases in the group of participants receiving the active plant extracts |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Laboratory of Reproductive Biology | Horsens | 8700 | Denmark |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25275520 | Derived | Fedder MD, Jakobsen HB, Giversen I, Christensen LP, Parner ET, Fedder J. An extract of pomegranate fruit and galangal rhizome increases the numbers of motile sperm: a prospective, randomised, controlled, double-blinded trial. PLoS One. 2014 Oct 2;9(9):e108532. doi: 10.1371/journal.pone.0108532. eCollection 2014. |
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| Placebo | Dietary Supplement | Tablets, two in the morning and two in the evening |
|
| Each participant is given plant extract for three months with flanking semen analyses. |