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| Name | Class |
|---|---|
| HarvestPlus | OTHER |
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The purpose of this study is to determine whether beans bred to have a high iron content are effective in improving the iron status of young women.
The goal of the study is to determine the efficacy of biofortified beans in improving the iron status of young women in Rwanda.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High iron bean | Active Comparator | High-iron bean |
|
| Low iron bean | Placebo Comparator | Low-iron bean |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Biofortified beans | Other | Comparison of two types of the common bean that are similar in all aspects except their iron concentration - one has a high iron concentration while the other has low iron concentration |
| Measure | Description | Time Frame |
|---|---|---|
| Improved iron status | Improvement in serum ferritin | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Improved physical and cognitive performance | Tests on physical performance using accelerometers and breath tests; cognitive tests | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Richard F. Hurrell, PhD | ETH Zurich | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National University of Rwanda | Butare | Kigali | Rwanda | |||
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32006009 | Derived | Luna SV, Pompano LM, Lung'aho M, Gahutu JB, Haas JD. Increased Iron Status during a Feeding Trial of Iron-Biofortified Beans Increases Physical Work Efficiency in Rwandan Women. J Nutr. 2020 May 1;150(5):1093-1099. doi: 10.1093/jn/nxaa016. | |
| 30926992 | Derived | Wenger MJ, Rhoten SE, Murray-Kolb LE, Scott SP, Boy E, Gahutu JB, Haas JD. Changes in Iron Status Are Related to Changes in Brain Activity and Behavior in Rwandan Female University Students: Results from a Randomized Controlled Efficacy Trial Involving Iron-Biofortified Beans. J Nutr. 2019 Apr 1;149(4):687-697. doi: 10.1093/jn/nxy265. |
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| ID | Term |
|---|---|
| D000090463 | Iron Deficiencies |
| ID | Term |
|---|---|
| D019189 | Iron Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| BEAN | Other | Placebo |
|
| Kigali |
| Kigali |
| Rwanda |
| 28954841 | Derived | Murray-Kolb LE, Wenger MJ, Scott SP, Rhoten SE, Lung'aho MG, Haas JD. Consumption of Iron-Biofortified Beans Positively Affects Cognitive Performance in 18- to 27-Year-Old Rwandan Female College Students in an 18-Week Randomized Controlled Efficacy Trial. J Nutr. 2017 Nov;147(11):2109-2117. doi: 10.3945/jn.117.255356. Epub 2017 Sep 27. |
| 27358417 | Derived | Haas JD, Luna SV, Lung'aho MG, Wenger MJ, Murray-Kolb LE, Beebe S, Gahutu JB, Egli IM. Consuming Iron Biofortified Beans Increases Iron Status in Rwandan Women after 128 Days in a Randomized Controlled Feeding Trial. J Nutr. 2016 Aug;146(8):1586-92. doi: 10.3945/jn.115.224741. Epub 2016 Jun 29. |