Resin Infiltration to Arrest Early Tooth Decay

Radiographic Progression of Early Caries Lesions After Resin Infiltration

The purpose of this study is to determine whether lesion infiltration is an effective management strategy to arrest early tooth decay.

A 3-year prospective, randomized control clinical trial (RCT) is designed incorporating a split mouth intra-oral design. Young volunteers (18-24 years old) with at least two early lesions in posterior teeth will be enrolled into this clinical trial to evaluate the clinical effectiveness of arresting lesion progression by resin infiltration therapy as adjunct to standard-of-care preventative measures. Lesion status (non-cavitated) is clinically confirmed prior to implementing the assigned therapy.

Inclusion Criteria:

• DMFT ≥ 3 (DMFT = index of decayed-missing-filled permanent teeth)
• Having at least two early caries lesions in approximal posterior tooth surfaces
• Lesions visible on radiograph

Exclusion Criteria:

• Current participation in another clinical study
• Medically compromised subjects
• Hyposalivation
• Pregnancy
• Allergic to methylmethacrylates
• Allergic to latex
• Symptomatic teeth