(Apex) Multicenter, Randomized, Active-Controlled Efficacy And Safety Study Comparing Extended Duration Betrixaban With Standard Of Care Enoxaparin For The Prevention Of Venous Thromboembolism In Acute Medically Ill Patients
(Apex) Multicenter, Randomized, Active-Controlled Efficacy And Safety Study Comparing Extended Duration Betrixaban With Standard Of Care Enoxaparin For The Prevention Of Venous Thromboembolism In Acute Medically Ill Patients
The purpose of this study is to evaluate whether extended prophylaxis with oral betrixaban can prevent blood clots in the leg and lung that sometime occur in patients hospitalized for an acute medical illness and to compare these results with standard of care enoxaparin. The safety of betrixaban will also be studied.
Inclusion Criteria:
men and non-pregnant, non-breastfeeding women
anticipated to be severely immobilized for at least 24 hours after randomization
hospitalized with one of the following
Exclusion Criteria:
Coronel Suarez, Buenos Aires, B7540DOL, Argentina
Rosario, Santa Fe, S2000DSV, Argentina
Leper, 8900, Belgium
Belo Horizonte - MG, 30150-221, Brazil
Brasilia/DF, 70710-905, Brazil
Campinas, Sao Paulo, 13059-740, Brazil
Curitiba - PR, 80030-001, Brazil
Porto Alegre/RS, 90620-001, Brazil
Salvador/BA, 40140-110, Brazil
Salvador/BA, 41810-011, Brazil
São José Do Rio Preto- SP, 15090-000, Brazil
Ontario, N8X 5A6, Canada
Plzen - Bory, 305 99, Czechia
Saint-Priest En Jarrez, 42055, France
Bad Friedrichshall, 74173, Germany
Karlbad, 76307, Germany
Möchengladbach, 41063, Germany
Hódmezövásárhely, 6800, Hungary
Frenze, 50134, Italy
Vittorio Veneto TV, 31029, Italy
Picayune, MS 39466, Montserrat
Lubertsy, 140006, Russia