A Phase 3 Randomized, Double-Blind Active-Controlled (Enoxaparin), Parallel-Group, Multi-Center Study to Evaluate the Safety and Efficacy of Oral Apixaban in Subjects Undergoing Elective Total Knee Replacement Surgery
A Phase 3 Randomized, Double-Blind Active-Controlled (Enoxaparin), Parallel-Group, Multi-Center Study to Evaluate the Safety and Efficacy of Oral Apixaban in Subjects Undergoing Elective Total Knee Replacement Surgery
The purpose of this study is to learn if apixaban can prevent blood clots in the leg (deep vein Thrombosis [DVT]) and lung (pulmonary embolism [PE]) that sometimes occur after knee replacement surgery and to learn how apixaban compares to enoxaparin (Lovenox®) for preventing these clots. The safety of apixaban will also be studied.
Key Inclusion Criteria:
Key Exclusion Criteria:
Buenos Aires, Buenos Aires 1280, Argentina
Buenos Aires, Buenos Aires 1425, Argentina
Buenos Aires, Buenos Aires 7540, Argentina
Buenos Aires, Buenos Aires C1181, Argentina
Capital Federal, Buenos Aires 1012, Argentina
Capital Federal, Buenos Aires 1426, Argentina
Dartmouth, Ontario B2Y 2N6, Canada
Kopenhamn S, 2300, Denmark
Df, Mexico City 01030, Mexico
Df, Mexico City 05300, Mexico
Df, Mexico City 07760, Mexico