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The malodour generation of a person's armpit/foot is caused by the bacteria thriving on that armpit/foot. In order to alter or reduce once bad body odour or foot odour, the living microbial community on the foot/armpit of a non-malodorous person will be transmitted (or up scaled and transmitted) to the foot/armpit of a malodorous person. The odour is evaluated by a trained smelling panel, the bacteria living on the armpit/foot is examined by means of molecular techniques. The microbial transplantation and its follow-up happens under the supervision of a doctor.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Heavy armpit odour | Experimental | Subjects with heavy armpit odour. |
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| Heavy foot odour | Experimental | Subjects with heavy foot odour. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Microbial transplant | Biological | Every subjects has 2 armpits and 2 feet. One armpit/foot is treated, the other is not treated. |
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| Measure | Description | Time Frame |
|---|---|---|
| Change in odour severity after bacterial transplantation | Odour evaluation by a trained smelling panel. | Baseline and day 1 |
| Change in odour severity after bacterial transplantation | Odour evaluation by a trained smelling panel. | Baseline and day 2 |
| Change in odour severity after bacterial transplantation | Odour evaluation by a trained smelling panel. | Baseline and day 3 |
| Change in odour severity after bacterial transplantation | Odour evaluation by a trained smelling panel. | Baseline and day 4 |
| Change in odour severity after bacterial transplantation | Odour evaluation by a trained smelling panel. | Baseline and day 5 |
| Change in odour severity after bacterial transplantation | Odour evaluation by a trained smelling panel. | Baseline and week 2 |
| Change in odour severity after bacterial transplantation | Odour evaluation by a trained smelling panel. | Baseline and week 3 |
| Change in odour severity after bacterial transplantation | Odour evaluation by a trained smelling panel. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in odour severity after bacterial transplantation | Odour evaluation by a trained smelling panel. | Baseline and 2 months |
| Change in odour severity after bacterial transplantation | Odour evaluation by a trained smelling panel. |
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Inclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jo Lambert, MD, PhD | University Hospital, Ghent | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ghent University | Ghent | Belgium |
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| Baseline and week 4 |
| Change in molecular characterisation of the bacterial community. | Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis (DGGE). | Baseline and day 1 |
| Change in molecular characterisation of the bacterial community. | Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis (DGGE). | Baseline and day 2 |
| Change in molecular characterisation of the bacterial community. | Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis (DGGE). | Baseline and day 3 |
| Change in molecular characterisation of the bacterial community. | Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis (DGGE). | Baseline and day 4 |
| Change in molecular characterisation of the bacterial community. | Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis (DGGE). | Baseline and day 5 |
| Change in molecular characterisation of the bacterial community. | Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis (DGGE). | Baseline and week 2 |
| Change in molecular characterisation of the bacterial community. | Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis (DGGE). | Baseline and week 3 |
| Change in molecular characterisation of the bacterial community. | Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis (DGGE). | Baseline and week 4 |
| Baseline and 4 months |
| Change in odour severity after bacterial transplantation | Odour evaluation by a trained smelling panel. | Baseline and 6 months |
| Change in molecular characterisation of the bacterial community | Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis (DGGE). | Baseline and 2 months |
| Change in molecular characterisation of the bacterial community | Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis (DGGE). | Baseline and 4 months |
| Change in molecular characterisation of the bacterial community | Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis (DGGE). | Baseline and 6 months |