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| Name | Class |
|---|---|
| Long Island University | OTHER |
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Hypothesis: The group of cervicogenic headache patients receiving upper cervical and upper thoracic thrust manipulation will demonstrate significant and clinically important changes in outcomes when compared to the mobilization and exercise group.
Patients with cervicogenic headache will be randomized to receive 6-8 sessions over 2-4 weeks of either: (1) upper cervical and upper thoracic thrust manipulation, or (2) upper cervical and upper thoracic non-thrust mobilization and range of motion, strength and postural exercises.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Thrust manipulation | Experimental |
| |
| Non-thrust mobilization and exercise | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Thrust Manipulation | Other | Upper cervical and upper thoracic thrust manipulation for 6-8 sessions over 2-4 weeks. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Headache Frequency | The number of headache days in the past week (as registered in headache diary) | Baseline |
| Headache Frequency | The number of headache days in the past week (as registered in headache diary) | 1-week |
| Headache Frequency | The number of headache days in the past week (as registered in headache diary) | 4-weeks |
| Headache Frequency | The number of headache days in the past week (as registered in headache diary) | 3-months |
| Headache Intensity | Average pain intensity as measured by the Numeric Pain Rating Scale (NPRS) per headache episode in the past week. | Baseline |
| Headache Intensity | Average pain intensity as measured by the Numeric Pain Rating Scale (NPRS) per headache episode in the past week. | 1-week |
| Headache Intensity | Average pain intensity as measured by the Numeric Pain Rating Scale (NPRS) per headache episode in the past week. | 4-weeks |
| Headache Intensity | Average pain intensity as measured by the Numeric Pain Rating Scale (NPRS) per headache episode in the past week. |
| Measure | Description | Time Frame |
|---|---|---|
| Global Rating of Change (GROC) | Perceived improvement. | 1-week |
| Global Rating of Change (GROC) | Perceived improvement. | 4-weeks |
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Inclusion Criteria:
Exclusion Criteria:
Bilateral headaches
Presence of any of the following atherosclerotic risk factors: hypertension, diabetes, heart disease, stroke, transient ischemic attack, peripheral vascular disease, smoking, hypercholesterolemia or hyperlipidemia
Red flags noted in the patient's Neck Medical Screening Questionnaire (i.e. tumor, fracture, metabolic diseases, RA, osteoporosis, prolonged history of steroid use, etc.)
History of whiplash injury within the last 6 weeks
Diagnosis of cervical spinal stenosis
Bilateral upper extremity symptoms
Evidence of central nervous system involvement, to include hyperreflexia, sensory disturbances in the hand, intrinsic muscle wasting of the hands, unsteadiness during walking, nystagmus, loss of visual acuity, impaired sensation of the face, altered taste, the presence of pathological reflexes (i.e. positive Hoffman's and/or Babinski reflexes)
Two or more positive neurologic signs consistent with nerve root compression, including any two of the following:
Prior surgery to the neck or thoracic spine.
Involvement in litigation or worker's compensation regarding their neck pain and/or headaches.
Physical therapy or chiropractic treatment for neck pain or headache in the 3 months before baseline examination.
Any condition that might contraindicate spinal manipulative therapy
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| Name | Affiliation | Role |
|---|---|---|
| Marshall Hagins, PT, PhD | Long Island University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Alabama Physical Therapy & Acupuncture | Montgomery | Alabama | 36117 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 21979312 | Background | Dunning JR, Cleland JA, Waldrop MA, Arnot CF, Young IA, Turner M, Sigurdsson G. Upper cervical and upper thoracic thrust manipulation versus nonthrust mobilization in patients with mechanical neck pain: a multicenter randomized clinical trial. J Orthop Sports Phys Ther. 2012 Jan;42(1):5-18. doi: 10.2519/jospt.2012.3894. Epub 2011 Sep 30. | |
| 26852024 |
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| ID | Term |
|---|---|
| D051298 | Post-Traumatic Headache |
| D006261 | Headache |
| D019547 | Neck Pain |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D051271 | Headache Disorders, Secondary |
| D020773 | Headache Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| ID | Term |
|---|---|
| D015444 | Exercise |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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| Non-thrust Mobilization and Exercise | Other | Upper cervical and upper thoracic non-thrust mobilization and exercise for 6-8 sessions over 2-4 weeks. |
|
|
| 3-months |
| Headache Duration | Average number of headache hours in the last week (as registered in the headache diary) | Baseline |
| Headache Duration | Average number of headache hours in the last week (as registered in the headache diary) | 1-week |
| Headache Duration | Average number of headache hours in the last week (as registered in the headache diary) | 4-weeks |
| Headache Duration | Average number of headache hours in the last week (as registered in the headache diary) | 3-months |
| Neck Disability Index (NDI) | Neck pain and disability | Baseline |
| Neck Disability Index (NDI) | Neck pain and disability | 1-week |
| Neck Disability Index (NDI) | Neck pain and disability | 4-weeks |
| Neck Disability Index (NDI) | Neck pain and disability | 3-months |
| Global Rating of Change (GROC) | Perceived improvement. | 3-months |
| Analgesic Use | Analgesic (medication intake) use per day (as registered in the headache diary). | Baseline |
| Analgesic Use | Analgesic (medication intake) use per day (as registered in the headache diary). | 3-months |
| Dunning JR, Butts R, Mourad F, Young I, Fernandez-de-Las Penas C, Hagins M, Stanislawski T, Donley J, Buck D, Hooks TR, Cleland JA. Upper cervical and upper thoracic manipulation versus mobilization and exercise in patients with cervicogenic headache: a multi-center randomized clinical trial. BMC Musculoskelet Disord. 2016 Feb 6;17:64. doi: 10.1186/s12891-016-0912-3. |
| D009422 | Nervous System Diseases |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001519 | Behavior |