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The purpose of this study is to determine the effect of three times a day mastication, during a follow-up period of 4 weeks, of two sugar-substituted chewing gums on various factors associated with dental caries and gingivitis.
The purpose of this paper is to compare the effect of daily consumption of two sugar-free chewing gum, one with Recaldent and one with Xylitol, added to traditional hygiene (brushing, fluoridated toothpaste and dental floss), in clinical features such as the accumulation of plaque and gingival inflammation, microbiological characteristics of saliva as the counts of cariogenic microorganisms and facultative anaerobes, and some physicochemical properties of saliva such as pH and concentrations of calcium and inorganic phosphate.
To this there was a general call among dental students at the University of Antioquia and those who expressed their intention to participate voluntarily with informed consent, were examined clinically and randomly assigned to one of the study groups (Recaldent or Xylitol) or the control group.
After a month of baseline examination and the daily use of the same instruments of oral hygiene and chewing of 6 pellets of each chewing gum (in the case of study groups), all variables are re-examined.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| sugar substituted chewing gum A | Experimental |
| |
| Sugar substituted chewing gum B | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| xylitol | Dietary Supplement | 6 g/day, for a month, by chewing 2g three times daily after meals. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Turesky index | dental plaque assessment | a month |
| Measure | Description | Time Frame |
|---|---|---|
| Gingival index | gingival inflammation | a month |
| salivary pH | a month | |
| Streptococcus mutans |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Maria C MartÃnez-Pabón, MsC Microb | Universidad de Antioquia | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Facultad de OdontologÃa, Universidad de Antioquia | MedellÃn | Antioquia | Colombia |
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| ID | Term |
|---|---|
| D003773 | Dental Plaque |
| D005891 | Gingivitis |
| ID | Term |
|---|---|
| D003741 | Dental Deposits |
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
| D007239 | Infections |
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| ID | Term |
|---|---|
| D014993 | Xylitol |
| D013402 | Sugar Alcohols |
| ID | Term |
|---|---|
| D000438 | Alcohols |
| D009930 | Organic Chemicals |
| D002241 | Carbohydrates |
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| casein phosphopeptide amorphous calcium phosphate complex | Dietary Supplement | two pieces of the commercial presentation three times daily after meals |
|
|
number of Streptococcus mutans in saliva |
| a month |
| Ca levels | levels of calcium in saliva | a month |
| facultative microorganisms | number of facultative microorganisms in saliva | a month |
| Lactobacillus | levels of Lactobacillus spp. in saliva | a month |
| phosphate levels | inorganic phosphate leves in saliva | a month |
| BOP index | bleeding on probing | a month |
| D005882 |
| Gingival Diseases |
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |