Role of the Stress in the Development of the Metabolic Syndrome

Role of Anxiety, Depression, Quality of Life and Stressful Vital Events in the Development of the Metabolic Syndrome. StreX Project.

The purpose of this study is determine the incidence of metabolic syndrome (MetS) in people of high risk, of 40 or more years and attended in the Primary Care. Evaluating the association between anxiety, depression, quality of life and the vital stressful events, and the development of the metabolic syndrome in general population.

Our hypothesis is that population of the cohort with bigger degree of stress will develop earlier the metabolic syndrome.

If our hypothesis about the metabolic syndrome are demonstrated, it would allow establishing in a future interventions on these factors of risk to prevent or to decrease the incidence of this syndrome in the Primary Care.

Inclusion Criteria:

• Both genders, elderly than 40 years

• Subjects with 1 or 2 criteria of NCEP-ATPIII set for Metabolic Syndrome

  • Abdominal waist > 102 cm ( men ) or >88 cm ( women )
  • Blood Pressure ( >130/85 mmHg ) ( or else pharmacologic treatment of hypertension )
  • Hypertriglyceridaemia ( >150 mg/dl ) ( or else pharmacologic treatment )
  • HDL-cholesterol <40 mg/dl ( men ) or <50 mg/dl ( women ) ( or else treatment )
  • Fasting glucose > 110 mg/dl.

Exclusion Criteria:

• Metabolic Syndrome (NCEP-ATPIII defined)(3 criteria of above mentioned)
• Severe or terminal disease
• Severe mental disease that difficulties the follow-up