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| Name | Class |
|---|---|
| Coordenação de Aperfeiçoamento de Pessoal de Nível Superior. | OTHER_GOV |
| Conselho Nacional de Desenvolvimento Científico e Tecnológico | OTHER_GOV |
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Several impairing factors contribute to physical limitation in chronic obstructive pulmonary disease (COPD) as deconditioning, muscle dysfunction and physical inactivity. The available literature clearly indicates that these therapeutic targets benefit from exercise training in patients with COPD and, currently, the key point is not whether patients should or not exercise, but which is the specific contribution of each exercise modality to this population. About this topic, the characteristics of a physical training program to be offered to patients have been a point discussed among researchers in this field, although recently the high-intensity training has been recognized as superior in comparison to the low-intensity training. Literature also indicates that, in order to change the sedentary lifestyle of patients with COPD, long-term training programs are indicated. However, a doubt still remains: if long-term programs are one of the key points to reduce physical inactivity, it is not yet clear whether it is necessary to include high-intensity exercises in that long-term program. If the duration is the only factor influencing the outcomes of the program, thus the intensity of training could be reduced, increasing the adherence of patients to the protocol. Based on this hypothesis, the aim of this study is to compare the effects of two physical training protocols in a long-term rehabilitation program (6 months) in patients with COPD: a high-intensity protocol (based on endurance and resistive training) and a low-intensity protocol (based on callisthenic and breathing exercises training). It is expected that the results of this study contribute to the scientific literature by demonstrating whether low- and high-intensity training contribute equally to change the sedentary lifestyle of patients after a long-term exercise program.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Low-intensity training (LT) | Active Comparator |
| |
| High-intensity training (HT) | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Physical training | Other | Aerobic exercises (treadmill and cycloergometer): Initially, the intensity is targeted at 60% of maximal capacity and it increases weekly until 110% of maximal capacity. Exercises duration: at least, 20 minutes. Resistive exercises (multi gym station; muscle groups: biceps, triceps and quadriceps): Initially, the intensity is targeted at 70% of one maximum repetition (1RM) and it increases weekly until 121% of 1RM. Exercises duration: 3 sets of 8 repetitions. Both exercise training are performed 3 times per week during 6 months. |
| Measure | Description | Time Frame |
|---|---|---|
| Physical activity in daily life | Main variable: time spent in physical activities of at least moderate intensity (min/day) | Up to 4 years |
| Measure | Description | Time Frame |
|---|---|---|
| Functional exercise capacity | 6-minute walking test | Up to 4 years |
| Maximal exercise capacity | Incremental Shuttle Walking Test | Up to 4 years |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Fabio Pitta, PhD | Contact | +55 43 3371-2477 | fabiopitta@uol.com.br |
| Name | Affiliation | Role |
|---|---|---|
| Fabio Pitta, PhD | Laboratory of Research in Respiratory Physiotherapy, State University of Londrina, Brazil | Study Chair |
| Nidia A. Hernandes, MSc | Laboratory of Research in Respiratory Physiotherapy, State University of Londrina, Brazil |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital Universitário Norte do Paraná (University Hospital Regional North of Parana) | Recruiting | Londrina | Paraná | 86038-350 | Brazil |
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| ID | Term |
|---|---|
| D029424 | Pulmonary Disease, Chronic Obstructive |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D002908 | Chronic Disease |
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| ID | Term |
|---|---|
| D064797 | Physical Conditioning, Human |
| ID | Term |
|---|---|
| D015444 | Exercise |
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
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| Physical training | Other | Callisthenic and breathing exercises are performed during 1 hour, 3 times per week during 6 months. The exercises are divided in 7 different sets and the degree of difficulty of the exercises progresses according to the set. |
|
| Peripheral muscle force | 1-repetitium maximum and peak quadriceps torque | Up to 4 years |
| Respiratory muscle force | Maximal inspiratory and expiratory pressures | Up to 4 years |
| Body composition | Electrical Bioimpedance | Up to 4 years |
| Health-related quality of life | Chronic Respiratory Disease Questionnaire (CRDQ) | Up to 4 years |
| Functional status | London Chest Activity of Daily Living scale (LCADL) | Up to 4 years |
| Dyspnea sensation | Borg scale | Up to 4 years |
| Lung function | Post-bronchodilator simple spirometry | Up to 4 years |
| Thaís Sant´Anna, PT | Laboratory of Research in Respiratory Physiotherapy, State University of Londrina, Brazil | Principal Investigator |
| Karina C. Furlanetto, PT | Laboratory of Research in Respiratory Physiotherapy, State University of Londrina, Brazil | Principal Investigator |
| Leila Donária, PT | Laboratory of Research in Respiratory Physiotherapy, State University of Londrina, Brazil | Principal Investigator |
| D020969 |
| Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001519 | Behavior |
| D055687 |
| Musculoskeletal and Neural Physiological Phenomena |