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Primary To investigate whether peripheral predonditioning induced by brief, intermittent constriction of blood supply to an arm can reduce the incidence of perioperative myocardial ischemia in patients operated electively for infrarenal aortic aneurysm.
Secondary To investigate the impact of peripheral preconditioning on perioperative inflammatory response.
To investigate whether peripheral preconditoning can protect against perioperative myocardial infarction and reduced cardiac pump function.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Preconditioning and normal treatment | Active Comparator |
| |
| normal treatment | Placebo Comparator | Standard treatment |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| preconditioning | Procedure | peripheral preconditioning induced by brief, intermittent constriction of blood supply to an arm |
|
| Measure | Description | Time Frame |
|---|---|---|
| measurements of CKMB and Troponin T | 30 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Aalborg Hospital | Not yet recruiting | Aalborg | Aalborg | 9000 | Denmark |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36645250 | Derived | Liang F, Liu S, Liu G, Liu H, Wang Q, Song B, Yao L. Remote ischaemic preconditioning versus no remote ischaemic preconditioning for vascular and endovascular surgical procedures. Cochrane Database Syst Rev. 2023 Jan 16;1(1):CD008472. doi: 10.1002/14651858.CD008472.pub3. |
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| ID | Term |
|---|---|
| D001014 | Aortic Aneurysm |
| ID | Term |
|---|---|
| D000783 | Aneurysm |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D001018 | Aortic Diseases |
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| Normal surgery, with sham intervention without inflating arm cuff | Procedure |
|
| Aarhus University Hospital, Skejby | Recruiting | Aarhus | Aarhus N | 8200 | Denmark |
|