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| Name | Class |
|---|---|
| Hospital de Clinicas de Porto Alegre | OTHER |
| Conselho Nacional de Desenvolvimento CientÃfico e Tecnológico | OTHER_GOV |
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The purpose of this study is to evaluate the absorption of dietary supplement of vitamin D3 (cholecalciferol), through the variation of 25 (OH) D levels, as the fat content of the meal associated with the administration of the supplement.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Low fat Meal | Experimental | 50,000 UI vitamin D3 with low fat meal |
|
| Medium fat meal | Experimental | 50,000 UI vitamin D3 with medium fat meal |
|
| High fat meal | Experimental | 50,000 UI vitamin D3 with high fat meal |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Vitamin D3 | Dietary Supplement | Supplement of vitamin D3 |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in serum 25(OH)D at 14 day after intervention | 25(OH)D response to supplemental vitamin D3 | Change from baseline in serum 25(OH)D at 14 days |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in Parathyroid hormone at 14 days after intervention | Parathyroid hormone response to supplemental vitamin D3 | Change from baseline in Parathyroid hormone at 14 days |
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Inclusion Criteria:
Residents of the hospital clinics of Porto Alegre
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Tania W Furlanetto, PhD | Federal University of Health Science of Porto Alegre | Principal Investigator |
| Gustavo AM Faulhaber, PhD | Federal University of Health Science of Porto Alegre | Study Chair |
| Fabiana V Raimundo, MD | Federal University of Health Science of Porto Alegre | Study Chair |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22190928 | Background | Raimundo FV, Faulhaber GA, Menegatti PK, Marques Lda S, Furlanetto TW. Effect of High- versus Low-Fat Meal on Serum 25-Hydroxyvitamin D Levels after a Single Oral Dose of Vitamin D: A Single-Blind, Parallel, Randomized Trial. Int J Endocrinol. 2011;2011:809069. doi: 10.1155/2011/809069. Epub 2011 Dec 7. | |
| 15956 | Background |
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| ID | Term |
|---|---|
| D014808 | Vitamin D Deficiency |
| ID | Term |
|---|---|
| D001361 | Avitaminosis |
| D003677 | Deficiency Diseases |
| D044342 | Malnutrition |
| D009748 | Nutrition Disorders |
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| ID | Term |
|---|---|
| D002762 | Cholecalciferol |
| ID | Term |
|---|---|
| D002782 | Cholestenes |
| D002776 | Cholestanes |
| D013256 | Steroids |
| D000072473 | Fused-Ring Compounds |
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| Placebo | Dietary Supplement | Placebo |
|
| Avnur Z, Nathan I, Dvilansky A, Livne A. Plasma constituent (s) inhibiting platelet adhesiveness. Isr J Med Sci. 1977 Mar;13(3):264-71. |
| D009750 |
| Nutritional and Metabolic Diseases |
| D011083 |
| Polycyclic Compounds |
| D013261 | Sterols |
| D014807 | Vitamin D |
| D012632 | Secosteroids |
| D008563 | Membrane Lipids |
| D008055 | Lipids |