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Absence of patients for recruitment
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The purpose of this study is to determine whether cardiac resynchronization therapy (CRT) is superior to interventricular right ventricle (RV) septal pacing in respect of reverse remodeling (LV ESD) and morbidity in patients with less preserved (less than 45%) ejection fraction (EF), persistent/permanent atrial fibrillation (AF) who successfully received atrioventricular (AV) junction ablation ablation (100% pacemaker dependency)
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| CRT | Experimental |
| |
| pacemaker | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Implantation of CRT device | Device | RV lead of CRT system is implanted into the middle part of interventricular septum |
|
| Measure | Description | Time Frame |
|---|---|---|
| Left Ventricle End-Systolic Volume (LV ESV) | 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Rate of cardiovascular events (hospitalization for worsening heart failure) | 12 month | |
| Changes in Quality of Life (measured by Minnesota Living with Heart Failure Questionnaire) | 12 months | |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Almazov Federal Heart, Blood and Endocrinology Centre | Saint Petersburg | 197341 | Russia |
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| Implantation of conventional VVI(R) pacemaker | Device | RV lead is implanted into the middle part of interventricular septum |
|
| Changes in NYHA functional class measured by peak V O2 oxygen consumption and distance of 6-minute walk test |
| 12 months |
| Echocardiographic indexes of LV remodeling | 12 months |
| ID | Term |
|---|---|
| D006333 | Heart Failure |
| D001281 | Atrial Fibrillation |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D001145 | Arrhythmias, Cardiac |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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