Atrioventricular Node Ablation in Patients With Atrial Fibrillation and Moderate Chronic Heart Failure

Variant of Stimulation in Atrioventricular Node Ablation (VISTA) in Patients With Atrial Fibrillation and Moderate Chronic Heart Failure

The purpose of this study is to determine whether cardiac resynchronization therapy (CRT) is superior to interventricular right ventricle (RV) septal pacing in respect of reverse remodeling (LV ESD) and morbidity in patients with less preserved (less than 45%) ejection fraction (EF), persistent/permanent atrial fibrillation (AF) who successfully received atrioventricular (AV) junction ablation ablation (100% pacemaker dependency)

Inclusion Criteria:

• Age of 18-75 years
• CHF II-III NYHA
• Persistent/permanent AF requiring AV node ablation
• LVEF < 45%
• Signed informed consent
• Able to complete all testing required by the clinical protocol

Exclusion Criteria:

• Myocardial infarction or stroke less than 3 months prior to randomization
• Patients who require revascularization, radiofrequency ablation of pulmonary veins and substrate of AF
• The congenital and acquired heart diseases, LV aneurysm, which requires a surgical correction
• Active inflammatory and autoimmune diseases of a myocardium
• The thyrotoxicosis
• The diseases that limit life expectancy (cancer, tuberculosis, etc.)
• Contraindications to anticoagulants administration at CHADS2> 2
• Uncompliant patients