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The purpose of this study is to examine if a chronic dehydration is a risk factor for the developement or progression of some forms of glaucoma.
Glaucoma patients who are hospitalized for diurnal intraocular pressure measurements and glaucoma assessment are asked about their drinking habits. Objective evaluation of hydration status is assessed with the Body Composition Monitor (Fresenius). Retinal Vessel Analysis and Laser Doppler Flowmetry are investigated in subgroups.
The control group are also hospitalized patients who do not suffer from glaucoma.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| glaucoma | hospitalized glaucoma patients |
| |
| controls | hospitalized patients without glaucoma |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| alter drinking habits | Behavioral | if dehydration is apparent, more fluid intake is recommended |
|
| Measure | Description | Time Frame |
|---|---|---|
| Dehydration | The composition of a patient's body, in particular a patient's water content are determined with bioimpedance spectroscopy (Body Composition Monitor, FRESENIUS) | 4 years |
| Measure | Description | Time Frame |
|---|---|---|
| microvascular changes | To investigate differences in retinal vessel diameters measured with the Retinal Vessel Analyzer (RVA, IMEDOS) in glaucoma patients and controls | 4 years |
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Inclusion Criteria:
Exclusion Criteria:
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Glaucoma patients who are hospitalized for diurnal intraocular pressure measurements and glaucoma assessment.
Controls who are hospitalizes because of an other ophthalmic disease and do not suffer from glaucoma.
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| Name | Affiliation | Role |
|---|---|---|
| Karin R Pillunat, MD | University Eye Clinic Dresden | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Eye Clinic Dresden | Dresden | 01307 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24820045 | Derived | Pillunat KR, Ventzke S, Spoerl E, Furashova O, Stodtmeister R, Pillunat LE. Central retinal venous pulsation pressure in different stages of primary open-angle glaucoma. Br J Ophthalmol. 2014 Oct;98(10):1374-8. doi: 10.1136/bjophthalmol-2014-305126. Epub 2014 May 12. |
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| ID | Term |
|---|---|
| D003681 | Dehydration |
| D005901 | Glaucoma |
| ID | Term |
|---|---|
| D014883 | Water-Electrolyte Imbalance |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D010335 | Pathologic Processes |
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| D013568 | Pathological Conditions, Signs and Symptoms |
| D009798 | Ocular Hypertension |
| D005128 | Eye Diseases |