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| Name | Class |
|---|---|
| Teva Neuroscience, Inc. | INDUSTRY |
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The present pilot study is designed to assess the extent to which rasagiline may improve cognition in Parkinson's disease patients requiring dopaminergic therapy. The primary objective is to assess improvement in the Montreal Cognitive Assessment (MoCA) in patients who have been on rasagiline at 1mg daily for twelve weeks. The secondary objective is to assess changes in the SCOPA-COG, FAB, and UPDRS II & III at the end of week 14.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Treatment Group | Active Comparator | Treatment group will receive Rasagiline (Azilect) 1mg daily |
|
| Placebo Group | Placebo Comparator | will receive placebo daily |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Rasagiline/Placebo | Drug | Will receive placebo pills each day for the entire 14 weeks. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Montreal Cognitive Assessment | Best value is 30 and Worst Value is 0. Scores for a series of subscales are not combined for a total overall score. | 14 Weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Fernando L Pagan, MD | Georgetown University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | United States |
| Type | Date | Date Unknown |
|---|---|---|
| Release | Aug 17, 2018 | |
| Reset | Sep 12, 2018 | |
| Release | Mar 18, 2019 |
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| Rasagiline | Drug | 0.5 mg for two weeks, then 1 mg for 12 weeks. |
|
|
| Reset | Apr 8, 2019 |
| Release | Jun 28, 2019 |
| Reset | Jul 22, 2019 |
| Release | Jan 10, 2020 |
| Reset | Jan 23, 2020 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Aug 17, 2018 | Sep 12, 2018 | |||
| Mar 18, 2019 | Apr 8, 2019 | |||
| Jun 28, 2019 | Jul 22, 2019 | |||
| Jan 10, 2020 | Jan 23, 2020 |
| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |
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| ID | Term |
|---|---|
| C031967 | rasagiline |
| D000073893 | Sugars |
| ID | Term |
|---|---|
| D002241 | Carbohydrates |
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