Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The purpose of the study is to investigate whether different doses of caffeinated coffee consumption has acute effects on subjective appetite feelings, energy intake and biochemical markers related to appetite, inflammation and glucose metabolism compared to water consumption in normal weight and overweight/obese participants.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| coffee3 | Experimental |
| |
| coffee6 | Experimental |
| |
| water | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| coffee | Other | Comparison of different amounts of coffee |
|
| Measure | Description | Time Frame |
|---|---|---|
| energy intake ad libitum | 180 min after breakfast/drink consumption | |
| total energy intake | One day | |
| appetite feelings | fasting (-15 min) | |
| appetite feelings | immediately after breakfast/drink consumption (0 min) | |
| appetite feelings | 15 min after breakfast/drink consumption | |
| appetite feelings | 30 min after breakfast/drink consumption | |
| appetite feelings | 60 min after breakfast/drink consumption | |
| appetite feelings | 90 min after breakfast/drink consumption | |
| appetite feelings | 120 min after breakfast/drink consumption | |
| appetite feelings | 150 min after breakfast/drink consumption | |
| appetite feelings | 180 min after breakfast/drink consumption | |
| Measure | Description | Time Frame |
|---|---|---|
| % carbohydrates ad libitum | 180 min after breakfast/drink consumption | |
| % carbohydrates total day | One day | |
| % protein ad libitum |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Mary Yannakoulia, PhD | Harokopio University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Metabolic Unit of the Department of Nutrition and Dietetics, Harokopio University | Athens | 17671 | Greece |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 21346100 | Background | Gavrieli A, Yannakoulia M, Fragopoulou E, Margaritopoulos D, Chamberland JP, Kaisari P, Kavouras SA, Mantzoros CS. Caffeinated coffee does not acutely affect energy intake, appetite, or inflammation but prevents serum cortisol concentrations from falling in healthy men. J Nutr. 2011 Apr 1;141(4):703-7. doi: 10.3945/jn.110.137323. Epub 2011 Feb 23. | |
| 35961260 |
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D009765 | Obesity |
| D007249 | Inflammation |
| D050177 | Overweight |
| ID | Term |
|---|---|
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
Not provided
Not provided
| ID | Term |
|---|---|
| D003069 | Coffee |
| ID | Term |
|---|---|
| D028321 | Plant Preparations |
| D001688 | Biological Products |
| D045424 | Complex Mixtures |
| D001628 | Beverages |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| appetite hormones |
| fasting (-15 min) |
| appetite hormones | immediately after breakfast/drink consumption (0 min) |
| appetite hormones | 15 min after breakfast/drink consumption |
| appetite hormones | 30 min after breakfast/drink consumption |
| appetite hormones | 60 min after breakfast/drink consumption |
| appetite hormones | 90 min after breakfast/drink consumption |
| appetite hormones | 120 min after breakfast/drink consumption |
| appetite hormones | 150 min after breakfast/drink consumption |
| appetite hormones | 180 min after breakfast/drink consumption |
| markers of inflammation | fasting (-15 min) |
| markers of inflammation | immediately after breakfast/drink consumption (0 min) |
| markers of inflammation | 15 min after breakfast/drink consumption |
| markers of inflammation | 30 min after breakfast/drink consumption |
| markers of inflammation | 60 min after breakfast/drink consumption |
| markers of inflammation | 90 min after breakfast/drink consumption |
| markers of inflammation | 120 min after breakfast/drink consumption |
| markers of inflammation | 150 min after breakfast/drink consumption |
| markers of inflammation | 180 min after breakfast/drink consumption |
| markers of glucose metabolism | fasting (-15 min) |
| markers of glucose metabolism | immediately after breakfast/drink consumption (0 min) |
| markers of glucose metabolism | 15 min after breakfast/drink consumption |
| markers of glucose metabolism | 30 min after breakfast/drink consumption |
| markers of glucose metabolism | 60 min after breakfast/drink consumption |
| markers of glucose metabolism | 90 min after breakfast/drink consumption |
| markers of glucose metabolism | 120 min after breakfast/drink consumption |
| markers of glucose metabolism | 150 min after breakfast/drink consumption |
| markers of glucose metabolism | 180 min after breakfast/drink consumption |
| 180 min after breakfast/drink consumption |
| % protein total day | One day |
| % fat | 180 min after breakfast/drink consumption |
| % fat total day | One day |
| Perakakis N, Kokkinos A, Angelidi AM, Tsilingiris D, Gavrieli A, Yannakoulia M, Tentolouris N, Mantzoros CS. Circulating levels of five proglucagon-derived peptides in response to intravenous or oral glucose or lipids and to a mixed-meal in subjects with normal weight, overweight, and obesity. Clin Nutr. 2022 Sep;41(9):1969-1976. doi: 10.1016/j.clnu.2022.07.001. Epub 2022 Jul 19. |
| 23498899 | Derived | Gavrieli A, Fragopoulou E, Mantzoros CS, Yannakoulia M. Gender and body mass index modify the effect of increasing amounts of caffeinated coffee on postprandial glucose and insulin concentrations; a randomized, controlled, clinical trial. Metabolism. 2013 Aug;62(8):1099-106. doi: 10.1016/j.metabol.2013.02.003. Epub 2013 Mar 15. |
| D012816 |
| Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010335 | Pathologic Processes |
| D000066888 |
| Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |