Study of Early-stage Lung Adenocarcinoma for Early Detection and Effective Treatment Strategy

Prospective Study of Early-stage Lung Adenocarcinoma for Early Detection and Effective Treatment Strategy

to determine the values of imaging and genetic biomarkers for prediction of tumor aggressiveness and prognosis in patient with early stage lung adenocarcinoma to Identify unique copy number alteration in patient with early stage lung adenocarcinoma to evaluate the long-term change of ground-glass nodule combined with lung adenocarcinoma to suggest a guideline for planning an appropriate follow-up examination and management

Inclusion Criteria:

• A. Clinically and radiologically suspected lung adenocarcinoma
• B. Newly-diagnosed Stage I or II from the clinical work up including PET/CT
• C. Performance status of 0 to 1 on the ECOG scale
• D. Age 20 years or older
• E. Able to tolerable DECT imaging required by protocol
• F. Able to give study-specific informed consent

Exclusion Criteria:

• A. Prior malignancy
• B. planning of Definitive RTx 나 neoadjuvant CCRTx
• C. Poor cardiopulmonary reserve