Radiomic Assessment in NSCLC: Correlation Between Multiparametric Imaging Biomarkers and Genetic Biomarkers

Radiomic Assessment in NSCLC: Correlation Between Multiparametric Imaging Biomarkers and Genetic Biomarkers

The purpose of this study is to evaluate relationships between multiparametric imaging biomarkers and genetic analysis in NSCLC patients.

To evaluate relationships between multiparametric imaging biomarkers(CT, PET/CT, MRI) and genetic analysis in NSCLC patients

Inclusion Criteria:

• Suspected lung cancer on chest CT or histologically proven NSCLC
• Participant is being considered for the conventional/neoadjuvant/targeted chemotherapy or surgery
• At least one measurable primary or other intrathoracic lesion >= 2cm, according to RECIST
• Performance status of 0 to 2 on the ECOG scale
• Age 20 years or older
• Able to tolerable PET/CT and CT imaging required by protocol
• Able to undergo percutaneous needle biopsy before and after chemotherapy
• Able to give study-specific informed consent

Exclusion Criteria:

• Poorly controlled diabetes
• Contraindication for CT contrast agent