Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The cognitive and psychiatric comorbidities are crucial endpoints in epileptic patients. Among these comorbidities, the Attention-Deficit Hyperactivity Disorder (ADHD) accounts for one of the most important in terms of frequency and psychosocial and educational consequences.
In these conditions, our study was designed to estimate the sensitivity to changes of the different sub-scores of the ADHD rating Scale IV (ADHD RS IV) in epileptic patient. This will then optimize our methodological approach for a therapeutic trial.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Treated patients | Experimental | Patients for whom ADHD treatment is introduced at enrolment. Evolution of the ADHD Rating Scale-IV inattention subscore |
|
| Non treated patients | Experimental | Patients for whom no ADHD treatment is required at enrolment. Evolution of the ADHD Rating Scale-IV inattention subscore |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ADHD Rating Scale-IV | Other | ADHD Rating Scale-IV test |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Evolution of the ADHD rating scale IV inattention subscore | Evolution of the ADHD rating scale IV inattention subscore in treated versus non treated patients, after 12 to 16 weeks. | Change from baseline in ADHD rating scale IV inattention subscore at 12 to16 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Evolution of the ADHD rating scale IV global score | Evolution of the ADHD rating scale IV global score in treated versus non treated patients, after 12 to 16 weeks. | Change from baseline in ADHD rating scale IV global score at 12 to16 weeks |
| Evolution of the ADHD rating scale IV hyperactivity subscore |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Sylvain RHEIMS, MD | Service de Neurologie Fonctionnelle et Epileptologie, Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Service de Neurologie pédiatrique, CHU d'Amiens | Amiens | 80054 | France | |||
| Service de Neurologie Pédiatrique, CHU d'Angers |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26991745 | Result | Mercier C, Roche S, Gaillard S, Kassai B, Arzimanoglou A, Herbillon V, Roy P, Rheims S. Partial validation of a French version of the ADHD-rating scale IV on a French population of children with ADHD and epilepsy. Factorial structure, reliability, and responsiveness. Epilepsy Behav. 2016 May;58:1-6. doi: 10.1016/j.yebeh.2016.02.016. Epub 2016 Mar 15. |
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D004827 | Epilepsy |
| D001289 | Attention Deficit Disorder with Hyperactivity |
| ID | Term |
|---|---|
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D019958 | Attention Deficit and Disruptive Behavior Disorders |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ADHD Rating Scale-IV |
| Other |
ADHD Rating Scale-IV test |
|
Evolution of the ADHD rating scale IV hyperactivity subscore in treated versus non treated patients, after 12 to 16 weeks. |
| Change from baseline in ADHD rating scale IV hyperactivity subscore at 12 to16 weeks |
| Angers |
| 49033 |
| France |
| Service de Neurologie pédiatrique, CHU de Besançon | Besançon | 25030 | France |
| Unité de Neurologie de l'Enfant et de l'Adolescent, Hôpital Pellegrin | Bordeaux | 33076 | France |
| Institut des Epilepsies de l'Enfant et de l'Adolescent, Hôpital Femme Mère Enfant | Bron | 69677 | France |
| Service de Neurologie Fonctionnelle et Epileptologie, Hôpital Neurologique Pierre Wertheimer | Bron | 69677 | France |
| Service d'épileptologie pédiatrique, CHR de Chambéry | Chambéry | 73011 | France |
| Cabinet Médical du Dr ISNARD | Lyon | 69002 | France |
| Service de Neurologie pédiatrique, Hôpital de la Timone | Marseille | 13385 | France |
| Service de Neurologie Pédiatrique, Hôpital Robert-Debré | Paris | 75019 | France |
| Service de Neurologie pédiatrique, Hôpital Neckert-Enfants malades | Paris | 75743 | France |
| Service de Pédiatrie, Hôpital Sud | Rennes | 35203 | France |
| Centre Référent des Epilepsies Rares, Hôpital de Hautepierre | Strasbourg | 67098 | France |
| Service de Neurologie Pédiatrique, Hôpital des Enfants | Toulouse | 31059 | France |
| Service de Neurologie Pédiatrique, CHU de Tours | Tours | 37044 | France |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |