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| Name | Class |
|---|---|
| University of Zurich | OTHER |
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As a consequence of the increase in life expectancy, hepato-biliary surgeons have to deal with an emerging aged population, which has a potential higher risk for complication and worse long-term outcome. The investigators will be analyzing the liver function and outcome after right or extended right hepatectomy in patients over 70 years old.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Elderly | Patients more or equal to 70 years old |
| |
| Young | Patients less than 70 years old |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Right hepatectomy | Procedure | Right liver resection |
|
| Measure | Description | Time Frame |
|---|---|---|
| Morbidity | Any type of complication defined according to the Clavien-Dindo Classification of surgical complications. | 90 days |
| Measure | Description | Time Frame |
|---|---|---|
| Mortality | Patient death occuring 90 days post-operatively | 90 days |
| Liver failure | Defined according to the Belghiti 50-50 criteria for liver failure. |
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Inclusion Criteria:
Exclusion Criteria:
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All patients that will undergo right or extended right hepatectomy for benign or malignant diseases.
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| Name | Affiliation | Role |
|---|---|---|
| Emmanuel Melloul, MD | Department of Visceral Surgery, University Hospital CHUV, Lausanne, Switzerland | Principal Investigator |
| Nicolas Demartines, MD | Department of Visceral Surgery, University Hospital CHUV, Lausanne, Switzerland | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Visceral Surgery, University Hospital CHUV | Lausanne | CH-1012 | Switzerland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19638912 | Background | Clavien PA, Barkun J, de Oliveira ML, Vauthey JN, Dindo D, Schulick RD, de Santibanes E, Pekolj J, Slankamenac K, Bassi C, Graf R, Vonlanthen R, Padbury R, Cameron JL, Makuuchi M. The Clavien-Dindo classification of surgical complications: five-year experience. Ann Surg. 2009 Aug;250(2):187-96. doi: 10.1097/SLA.0b013e3181b13ca2. | |
| 19106687 |
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| ID | Term |
|---|---|
| D017114 | Liver Failure, Acute |
| ID | Term |
|---|---|
| D017093 | Liver Failure |
| D048550 | Hepatic Insufficiency |
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
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| Extended right hepatectomy | Procedure | Right hepatectomy involving 5 or more segments |
|
|
| 90 days |
| Hospital stay | Total hospital stay (including re-admission hospital stay) in days | 90 days |
| Paugam-Burtz C, Janny S, Delefosse D, Dahmani S, Dondero F, Mantz J, Belghiti J. Prospective validation of the "fifty-fifty" criteria as an early and accurate predictor of death after liver resection in intensive care unit patients. Ann Surg. 2009 Jan;249(1):124-8. doi: 10.1097/SLA.0b013e31819279cd. |