Safety of the CO-rebreathing Method in Stable Coronary Artery Disease and COPD Patients

Safety of the CO-rebreathing Method in Stable Coronary Artery Disease and COPD Patients

The primary objective is to establish the safety of the CO-rebreathing method for measuring total blood and plasma volume in CAD patients. The working hypothesis is that the CO-rebreathing method is safe in use with coronary artery disease patients and that it does not cause myocardial ischemia or cardiovascular damage.

Inclusion Criteria:

• Stable coronary artery disease
• Stable COPD
• Optimal medication

Exclusion Criteria:

• Unstable disease
• co-morbidities