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The purpose of this study is to evaluate of efficacy and safety of mometasone furoate plus azelastine HCl in patients with perennial allergic rhinitis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| mometasone furoate + azelastin HCl | Experimental | opaque suspension, four times each naris per day |
|
| mometasone furoate | Active Comparator | opaque suspension, four times each naris per day |
|
| azelastine HCl | Active Comparator | lucidus colorless liquid, two times each naris per day |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| mometasone furoate plus azelastine HCl | Drug |
|
| |
| Measure | Description | Time Frame |
|---|---|---|
| change from baseline in rTNSS(reflective Total Nasal Symptom Score) | 4 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| change from baseline in AM rTNSS(AM reflective Total Nasal Symptom Score) | 4 weeks | |
| change from baseline in PM rTNSS(PM reflective Total Nasal Symptom Score) | 4 weeks | |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Yang Gi Min, M.D. | Seoul National University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul National University Hospital | Seoul | 110-744 | South Korea |
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| mometasone furoate |
| Drug |
|
|
| azelastine HCl | Drug |
|
|
| change from baseline in iTNSS(instantaneous Total Nasal Symptom Score) |
| 4 weeks |
| change from baseline in AM iTNSS(AM instantaneous Total Nasal Symptom Score) | 4 weeks |
| change from baseline in PM iTNSS(PM instantaneous Total Nasal Symptom Score) | 4 weeks |
| ID | Term |
|---|---|
| D012221 | Rhinitis, Allergic, Perennial |
| ID | Term |
|---|---|
| D065631 | Rhinitis, Allergic |
| D012220 | Rhinitis |
| D009668 | Nose Diseases |
| D012140 | Respiratory Tract Diseases |
| D012130 | Respiratory Hypersensitivity |
| D010038 | Otorhinolaryngologic Diseases |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |
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| ID | Term |
|---|---|
| D000068656 | Mometasone Furoate |
| C020976 | azelastine |
| ID | Term |
|---|---|
| D011244 | Pregnadienediols |
| D011245 | Pregnadienes |
| D011278 | Pregnanes |
| D013256 | Steroids |
| D000072473 | Fused-Ring Compounds |
| D011083 | Polycyclic Compounds |
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