Pillcam colon capsule (PCC) endoscopy is a novel strategy tool to inspect colon mucosa. The aim of the present study is to evaluate if PCC endoscopy is able to precisely investigate patients with ulcerative colitis and reach high consistency to conventional colonoscopy.

Symptomatic patients with confirmed ulcerative colitis (UC) were enrolled in this prospective single-center study. No sooner had patients gone through Pillcam colon capsule (PCC) endoscopy solution than they got conventional colonoscopy which is recognized as the "gold standard" examination technique. The extent of mucosal damage and inflammatory lesions during both modalities were recorded for comparison. In addition, the regimen of bowel preparation, completion rate, colonic cleanliness, compliance or adverse events were analyzed.

Inclusion Criteria:

• Adult patients (aged 18-70)
• Ulcerative Colitis history
• Suffering from symptoms such as hematochezia, diarrhea or abdominal pain

Exclusion Criteria:

• Patients with a high risk for capsule retention (such as intestinal diverticula, acute abdominal pain without regular defecation indicating intestinal obstruction or a history of abdominal operation or intestinal reconstructed operation),
• Patients allergic to sodium phosphate or polyethylene glycol (PEG) solution,
• Patients with a history of Crohn's disease
• Patients with serious systematic diseases such as congestive heart failure, renal failure or severe liver disease.

academic hospital endoscopist of digestive department