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| Name | Class |
|---|---|
| Department of Medicine | AMBIG |
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The interest in studying the impact of aquatic exercise on muscle strength of patients with rheumatoid arthritis came after publication of several studies that pointed to the potential benefit of exercise on the natural history of the disease, including reduction of pain, better immune response as well as aerobic fitness and functional capacity and increase muscle strength, endurance and quality of life.
In general, the aquatic exercises are indicated for patients with chronic joint diseases, since the aquatic environment seems to be more secure for this population due to the reduction of joint loading, as well as gain range of motion.
However, there are some difficulties to show the real and consistent beneficial effect of physical activity in these patients, such as the small number of randomized controlled clinical trials, short intervention period (4-8 weeks), lack of details of the exercise protocols used, methodological problems (heterogeneous measures to evaluate the outcome, change of medication). Moreover, no study evaluated the disease activity, according to the tool most used clinically worldwide, the DAS28.
It is known that aquatic exercises without impact in healthy subjects are sufficient to gain muscle strength. Nonetheless, in people with joint limitation the benefits from these same exercises to gain muscle strength is not known.
To date, no studies addressing the effect of aquatic exercise on muscle strength and disease activity in patients with rheumatoid arthritis. In addition, there is the need to obtain a standardized protocol for prescribing of aquatic exercises. The choice of lower-limb strength was based on its relevance to the acceleration and deceleration during the march, as well as to perform activities of daily living, leisure and professional in these individuals.
Thus, this study aims at:
The investigators objectives are:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Land exercises | Placebo Comparator | The patients of this group will perform the same exercises from water exercises |
|
| Water exercises | Active Comparator | The patients of this group will perform the same exercises from land exercises |
|
| Control group | No Intervention | No intervention will be recommended |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Land exercises | Procedure | 3 times a week. 50 minutes in every session. Performed by educational professor |
|
| Measure | Description | Time Frame |
|---|---|---|
| Muscle strength | Isokinetic muscle strength | 16 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Disease Activity Score (DAS28) | To evaluate the disease activity in rheumatoid arthritis | 16 weeks |
| Health Assessment Questionnaire (HAQ) | To measure the impact of funcional capacity in patients with rheumatoid arthritis |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Marcelo M Pinheiro, MD, PhD | Federal University of São Paulo | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Federal University of Sao Paulo | São Paulo | São Paulo | 04042033 | Brazil |
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| ID | Term |
|---|---|
| D001172 | Arthritis, Rheumatoid |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D012216 | Rheumatic Diseases |
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| Water exercises | Procedure | 3 times a week. 50 minutes in every session. Performed by educational professor |
|
| 16 weeks |
| Body composition measurements | Measures of body composition (lean and fat mass), by Dual-X ray absorptiometry (DXA) | 16 weeks |
| D003240 |
| Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
| D001519 | Behavior |