Risk Prediction in Aortic Stenosis

Risk Prediction in Aortic Stenosis by Cardiac Autonomic Function

The purpose of this study is to test the prognostic value of autonomic markers in patients with aortic stenosis.

Autonomic function will be assessed by presence of severe autonomic failure (defined by combination of abnormal heart rate turbulence and deceleration capacity).

Autonomic function will also be assessed by respiration and repolarization abnormalities.

Inclusion Criteria:

• Aortic valve area ≤1.5 qcm or mean aortic gradient ≥25mmHg

Exclusion Criteria:

• life expectancy <1 year due to non-cardiac causes