Effect of Saccharomyces Boulardii on Indirect Hyperbilirubinemia and Phototherapy Duration in Very Low Birth Weight Infants

Phase 4 Study of Saccharomyces Boulardii on Indirect Hyperbilirubinemia

Indirect hyperbilirubinemia is frequently observed in premature infants.Probiotics are favorable microorganisms that regulate the flora of the gastrointestinal system. In this study we aimed to compare the effect of S. boulardii on severity of hyperbilirubinemia and duration of phototherapy on very low birth weight infants.

Inclusion Criteria:

• very low birth weight infants

Exclusion Criteria:

• chromosomal anomalies