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| Name | Class |
|---|---|
| University of Erlangen-Nürnberg | OTHER |
| Institute of Physical Education and Sports Sciences | OTHER |
| Klinikum Nürnberg | OTHER |
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The purpose of the study is to determine the effect of 16 weeks of running exercise on various parameters related to heart, vascular systems, blood, and muscle in untrained males 30-50 years old.
Further, the investigators assess which of the above mentioned parameters may explain the increase of running performance most accurate.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| exercise | Experimental | 16 weeks of running exercise |
|
| control | No Intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| exercise | Other | 16 week of periodized progressive running exercise 2-4 times/week |
|
| Measure | Description | Time Frame |
|---|---|---|
| myocardial mass/stroke volume | Atrial and ventricular volume and mass indexes were assessed by magnetic resonance imaging (MRI) | 4 month |
| Measure | Description | Time Frame |
|---|---|---|
| maximal oxygen uptake | maximal oxygen uptake during running | 4 month |
| Resting metabolic rate | Adaptation of resting metabolic rate to running exercise |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Michael Lell, MD | Departement of Radiology, Division of Cardiology, University of Erlangen-Nurnberg | Study Director |
| Michael Scharf, MD | Departement of Radiology, Division of Cardiology | Principal Investigator |
| Willi A Kalender, PhD | Institute of Medical Physics, University of Erlangen, Germany | Study Chair |
| Michael Uder, MD | Departement of Radiology, University of Erlangen-Nurnberg | Study Chair |
| Wolfgang Kemmler, PhD | Institute of Medical Physics, University of Erlangen-Nurnberg, Germany | Study Director |
| Simon von Stengel, PhD | University of Erlangen-Nürnberg Medical School | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Institute of Medical Physics, University of Erlangen-Nurnberg | Erlangen | 91052 | Germany | |||
| Institute of Physical Education and Sport Sciences |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 20807850 | Background | Scharf M, Brem MH, Wilhelm M, Schoepf UJ, Uder M, Lell MM. Atrial and ventricular functional and structural adaptations of the heart in elite triathletes assessed with cardiac MR imaging. Radiology. 2010 Oct;257(1):71-9. doi: 10.1148/radiol.10092377. Epub 2010 Aug 31. | |
| 33345059 | Derived | Tuttor M, von Stengel S, Kohl M, Lell M, Scharf M, Uder M, Wittke A, Kemmler W. High Intensity Resistance Exercise Training vs. High Intensity (Endurance) Interval Training to Fight Cardiometabolic Risk Factors in Overweight Men 30-50 Years Old. Front Sports Act Living. 2020 Jun 16;2:68. doi: 10.3389/fspor.2020.00068. eCollection 2020. |
| Label | URL |
|---|---|
| homepage of the Institute of Medical Physical with study informations. | View source |
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| ID | Term |
|---|---|
| D006332 | Cardiomegaly |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D006984 | Hypertrophy |
| D020763 | Pathological Conditions, Anatomical |
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| ID | Term |
|---|---|
| D015444 | Exercise |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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| 4 month |
| muscle strength/power | Isometric muscle strength of the leg extensors Leg power as assessed by counter movement jump | 4 month |
| myocardial volume | Functional and morphologic parameters of the heart as assessed by echocardiography | 4 month |
| Intima media thickness | Carotid intima media thickness by high-resolution ultrasound | 4 month |
| Erlangen |
| 91052 |
| Germany |
| Departement of Radiology, University of Erlangen-Nurnberg | Erlangen | 91054 | Germany |
| 25873721 | Derived | Scharf M, Schmid A, Kemmler W, von Stengel S, May MS, Wuest W, Achenbach S, Uder M, Lell MM. Myocardial adaptation to high-intensity (interval) training in previously untrained men with a longitudinal cardiovascular magnetic resonance imaging study (Running Study and Heart Trial). Circ Cardiovasc Imaging. 2015 Apr;8(4):e002566. doi: 10.1161/CIRCIMAGING.114.002566. |
| D013568 |
| Pathological Conditions, Signs and Symptoms |