Biochemical Markers and 2 and 3D Ultrasound to ID Maternal & Fetal Complications

The Combination of Biochemical Markers and Two and Three Dimensional Ultrasound Using Geometric Morphometrics in the Identification of Congenital Anomalies and Maternal or Fetal Complications

Can a combination of prenatal screening blood tests, early ultrasound, and a 3D ultrasound of the fetal face at approximately 20 weeks gestation identify fetuses with congenital anomalies and predict maternal and fetal complications?

Pts will be consented upon presenting to the department for a comprehensive ultrasound.The 3D picture is the only part of the study that is not part of standard obstetrical care.

Inclusion Criteria:

• Pregnant women at approximately 20 weeks
• ages 18-50
• singleton pregnancy
• plans to deliver at North Shore University Hosp
• completed step-wise sequential screening

Exclusion Criteria:

• multifetal gestation
• minors
• patients who have undergone diagnostic genetic testing
• incarcerated patients
• intention to deliver at a hospital other than North Shore University hosp