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| Name | Class |
|---|---|
| The New Zealand Institute of Plant and Food Research Ltd. | OTHER_GOV |
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Hops have been used for many years for their supposed sedative and anxiety reducing properties and can be found in many natural remedies for stress, anxiety and sleeping that are already available to buy.
However, human trials investigating the effects of hops have so far been limited to the effects of the combination of hops and valerian in relation to sleep. Such studies have identified that a valerian-hops mixture can result in improved sleep but Valerian alone has no effect.
The current study aims to investigate the effect of hops alone in healthy human participants aged 18-35 years.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 102mg extract 1 hops | Active Comparator | Equivalent to 0.5g dry weight |
|
| 410mg extract 1 hops | Active Comparator | Equivalent to 2g dry weight |
|
| 79mg extract 2 hops | Active Comparator | Equivalent to 0.5g dry weight |
|
| 316mg extract 2 hops | Active Comparator | Equivalent to 2g dry weight |
|
| Placebo | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Hops Extract | Dietary Supplement | All 150 participants will complete 1 study visit; receiving either of the 4 hops doses or placebo (silica). Computer generated random numbers will be used to allocate treatments to participant identification numbers. Treatment will be administered in capsule form and in a double blind manner. |
| Measure | Description | Time Frame |
|---|---|---|
| Mood |
| across 3 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Satiety |
| across 3 hours |
| Bioavailability of Hops |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Crystal Haskell | Northumbria University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Northumbria University | Newcastle upon Tyne | NE1 8ST | United Kingdom |
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| ID | Term |
|---|---|
| C548267 | ALPL protein, human |
| D012822 | Silicon Dioxide |
| ID | Term |
|---|---|
| D008903 | Minerals |
| D007287 | Inorganic Chemicals |
| D010087 | Oxides |
| D017601 | Oxygen Compounds |
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|
| Placebo (silica) | Other | All 150 participants will complete 1 study visit; receiving either of the 4 hops doses or placebo (silica). Computer generated random numbers were used to allocate treatments to participant identification numbers. Treatment will be administered in capsule form and in a double blind manner. |
|
• Plasma hops levels are to be examined to assess bioavailability.
| across 3 hours |
| Cognition |
| across 3 hours |
| D017655 |
| Silicon Compounds |