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| Name | Class |
|---|---|
| University of Toronto | OTHER |
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The current standard for pain relief during prostate biopsy is the injection of local anesthetic agents into or around the prostate at various sites including apex, base, lateral aspects and into the prostate itself. Despite such anesthetic injection, some men still experience severe pain and often at the base of the penis. The study audits current practices comparing the degree of pain relief provided by injection at basal versus basal+apical sites. All these injection sites are standard practice at our hospital.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| basal injection | Active Comparator | basal injection of anesthetics |
|
| basal + apical injection | Active Comparator | basal + apical injection of anesthetics |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| anesthetics injection | Procedure | Basal injection of anesthetics or basal + apical injection of anesthetics. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Pain scores comparing two groups. | Pain questionnaires will be asked to filled in before the procedure, within 20 minutes of the procedure, at 2-4 weeks and at 6-month post procedure. | post prostate biopsy procedure up to 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of side effects and complications. | Questionnaires will be asked to filled in to assess side effects and complications at 2-4 weeks and at 6-month post procedure. | post prostate biopsy procedure up to 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Ants Toi, MD | University Health Network, Toronto | Principal Investigator |
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| ID | Term |
|---|---|
| D010146 | Pain |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D000777 | Anesthetics |
| ID | Term |
|---|---|
| D002492 | Central Nervous System Depressants |
| D045505 | Physiological Effects of Drugs |
| D020228 | Pharmacologic Actions |
| D020164 | Chemical Actions and Uses |
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| D002491 | Central Nervous System Agents |
| D045506 | Therapeutic Uses |