This study assesses differences in the effects of pelvic plexus block and periprostatic nerve block among various anesthetic methods that reduce the pain caused by prostate biopsy.

Recently, various types of local anesthetic methods have been attempted to reduce biopsy-related pain leading to changes in the type of anesthetic agents and site of injection. Of these anesthetics and combinations, pelvic plexus block and periprostatic nerve block seem to be the very effective way to control prostate biopsy-related pain. However, few studies have compared these two methods.

Inclusion Criteria:

• abnormal prostate finding on digital rectal examination
• serum PSA level of > 2.5 ng/mL
• Transrectal ultrasonographic abnormal lesion

Exclusion Criteria:

• under 50 years old
• a history of previous TRUS-guided biopsy
• chronic prostatitis/pelvic pain
• neurological conditions (dementia, Parkinson disease, or cerebral infarction)
• bleeding diathesis
• active UTI
• hemorrhoids/anal fissure/anal fistula
• known allergy to lidocaine