Vascular and Periodontal Disease - Microbial, Genetic and Histological Causalities

Periodontal-, Cardiovascular- and Aneurysmal Diseases.

The purpose of this study is to analyze genetic polymorphisms in genes encoding pro-inflammatory cytokines, and study the genetic predisposition to chronic periodontitis (CP) in combination with atherosclerotic cardiovascular (ACD) and aneurysmal diseases. The investigators will also try to identify oral bacteria in atherosclerotic plaques and aneurysmal walls and thrombus. Histological analyses of atherosclerotic plaques and aneurysmal wall will be performed.

Inclusion Criteria:

• Patients undergoing vascular surgery at Oslo University Hospital, Aker, previously randomly collected patients with periodontitis,

Exclusion Criteria:

• patients whom undergone antibiotic treatment the past month.
• patients whom undergone periodontal treatment the past 6 months.
• patients with no teeth