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In previous study (MW2004-011-02), patients with burn wounds had their damaged skin removed by either standard of care treatment or by Debrase Gel Dressing (DGD), which is composed of enzymes that dissolve the damaged skin selectively (DGD removes only the damaged skin and not other parts of the skin).
The burn wound, like any other wound, heals by the formation of scar at the injured site in order to replace the destroyed tissues. Scarring is not a static process, but rather a dynamic one, changing over time, especially during the first 24 months post-injury.
Scars and patients' quality of life from two treatment arms (DGD and SOC) will be compared in order to evaluate the long term influence of damaged skin removal and wound care techniques on scar formation and maturation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients that were treated in MW2004-011-02 study with Debrase |
| ||
| Patients that were treated in MW2004-011-02 with SOC |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Scars assessment & QOL | Other | Scar assessment and quality of life questionnaires |
|
| Measure | Description | Time Frame |
|---|---|---|
| 1. Scar assessment of target wounds that have been treated by Debrase or SOC during MW2004-11-02 using Modified Vancouver Scar Scale (MVSS) | Assesment of scars will be done using the Modified Vancouver Scar Scale | Approximately 2 years after wound closure |
| 2. To evaluate and compare the Quality of Life (QoL) in adult and children that their burn wounds were treated with Debrase or SOC in study MW2004-11-02 | 2. A Quality of Life (QoL) assessment will be performed in burn victims using a Short Form 36 (SF-36) and Burn Outcomes Questionnaire (BOQ). | Approximately 2 years after wound closure |
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Inclusion criteria
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Patients that have previously participated in MW2004-011-02 study
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| Name | Affiliation | Role |
|---|---|---|
| Jan Koller, MD,PhD | Department Head of Burs and Reconstructive Surgery | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clinic of Burns and reconstructive surgery hospital | Košice | Slovakia |
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| ID | Term |
|---|---|
| D011788 | Quality of Life |
| ID | Term |
|---|---|
| D006304 | Health Status |
| D003710 | Demography |
| D015991 | Epidemiologic Measurements |
| D011634 | Public Health |
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| D004778 |
| Environment and Public Health |