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| Name | Class |
|---|---|
| Vichy Catalán, Spain | UNKNOWN |
Water consumption is essential to maintain hydration and good health. Sodium-bicarbonated mineral waters are reported to have beneficial digestive and hypocholesterolemic properties. The aim of this study was to investigate the effects of the consumption of a sodium-bicarbonated mineral water (BW) with or without a meal, compared to a low mineral content water as a control water (CW), on postprandial serum triacylglycerols (TAG), cholecystokinin (CCK), and gallbladder volume.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| BW | Experimental | Bicarbonated mineral water without meal |
|
| BW with meal | Experimental | Bicarbonated mineral water with meal |
|
| CW | Active Comparator | Mineral water low in mineral content (control) without meal |
|
| CW with meal | Active Comparator | Mineral water low in mineral content (control) with a meal |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bicarbonated mineral water | Dietary Supplement | Volunteers fasted overnight consumed: 0.5 L of the bicarbonated mineral water without meal or, 0.5 L of the bicarbonated mineral water with meal |
| Measure | Description | Time Frame |
|---|---|---|
| Serum triacylglycerols | Baseline | |
| Serum triacylglycerols | Postprandial 30 minutes | |
| Serum triacylglycerols | Postprandial 60 minutes | |
| Serum triacylglycerols | Postprandial 120 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Serum glucose | Baseline | |
| Serum glucose | Postprandial 30 minutes | |
| Serum glucose |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| M Pilar Vaquero, Dr | National Research Council, Spain | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Institute of Food Science, Technology and Nutrition (ICTAN), Spanish National Research Council (CISC) | Madrid | Madrid | 28040 | Spain |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 15113945 | Background | Schoppen S, Perez-Granados AM, Carbajal A, Oubina P, Sanchez-Muniz FJ, Gomez-Gerique JA, Vaquero MP. A sodium-rich carbonated mineral water reduces cardiovascular risk in postmenopausal women. J Nutr. 2004 May;134(5):1058-63. doi: 10.1093/jn/134.5.1058. | |
| 15877873 | Background | Schoppen S, Perez-Granados AM, Carbajal A, de la Piedra C, Pilar Vaquero M. Bone remodelling is not affected by consumption of a sodium-rich carbonated mineral water in healthy postmenopausal women. Br J Nutr. 2005 Mar;93(3):339-44. doi: 10.1079/bjn20041332. |
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| ID | Term |
|---|---|
| D002318 | Cardiovascular Diseases |
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| Mineral water low in mineral content (control) | Dietary Supplement | Volunteers fasted overnight consumed: 0.5 L of the control water without meal or, 0.5 L of the control water with meal |
|
| Postprandial time 60 minutes |
| Serum glucose | Postprandial time 120 minutes |
| Serum insulin | Baseline |
| Serum insulin | Postprandial 30 minutes |
| Serum insulin | Postprandial 60 minutes |
| Serum insulin | Postprandial 120 minutes |
| Cholecystokinin | Baseline |
| Cholecystokinin | Postprandial 30 minutes |
| Cholecystokinin | Postprandial 60 minutes |
| Cholecystokinin | Postprandial 120 minutes |
| Gallbladder volume | Baseline |
| Gallbladder volume | Postprandial 15 minutes |
| Gallbladder volume | Postprandial 30 minutes |
| Gallbladder volume | Postprandial 60 minutes |
| Gallbladder volume | Postprandial 120 minutes |
| Aldosterone | Baseline |
| Aldosterone | Postprandial 30 minutes |
| Aldosterone | Postprandial 60 minutes |
| Aldosterone | Postprandial 120 minutes |
| 16197584 | Background | Schoppen S, Perez-Granados AM, Carbajal A, Sarria B, Sanchez-Muniz FJ, Gomez-Gerique JA, Pilar Vaquero M. Sodium bicarbonated mineral water decreases postprandial lipaemia in postmenopausal women compared to a low mineral water. Br J Nutr. 2005 Oct;94(4):582-7. doi: 10.1079/bjn20051515. |
| 17886090 | Background | Schoppen S, Perez-Granados AM, Carbajal A, Sarria B, Navas-Carretero S, Pilar Vaquero M. Sodium-bicarbonated mineral water decreases aldosterone levels without affecting urinary excretion of bone minerals. Int J Food Sci Nutr. 2008 Jun;59(4):347-55. doi: 10.1080/09637480701560308. |
| 17970536 | Background | Schoppen S, Sanchez-Muniz FJ, Perez-Granados M, Gomez-Gerique JA, Sarria B, Navas-Carretero S, Pilar Vaquero M. Does bicarbonated mineral water rich in sodium change insulin sensitivity of postmenopausal women? Nutr Hosp. 2007 Sep-Oct;22(5):538-44. |
| 19954956 | Background | Perez-Granados AM, Navas-Carretero S, Schoppen S, Vaquero MP. Reduction in cardiovascular risk by sodium-bicarbonated mineral water in moderately hypercholesterolemic young adults. J Nutr Biochem. 2010 Oct;21(10):948-53. doi: 10.1016/j.jnutbio.2009.07.010. Epub 2009 Dec 1. |
| 20449535 | Background | Schoppen S, Perez-Granados AM, Navas-Carretero S, Vaquero MP. Postprandial lipaemia and endothelial adhesion molecules in pre- and postmenopausal Spanish women. Nutr Hosp. 2010 Mar-Apr;25(2):256-61. |
| 21913027 | Result | Toxqui L, Perez-Granados AM, Blanco-Rojo R, Vaquero MP. A sodium-bicarbonated mineral water reduces gallbladder emptying and postprandial lipaemia: a randomised four-way crossover study. Eur J Nutr. 2012 Aug;51(5):607-14. doi: 10.1007/s00394-011-0244-x. Epub 2011 Sep 13. |
| Result | Toxqui L, Pérez-Granados AM, Blanco-Rojo R, Vaquero MP. Effects of an alkaline mineral water on cholecystokinin levels and gallbladder emptying in young adults. Ann Nutr Metab 58(suppl 3):352-353,2011 |
| Result | Toxqui L, Pérez-Granados AM, Blanco-Rojo R, Vaquero MP. Sodium-bicarbonated mineral water reduces postprandial lipaemia in moderately hypercholesterolaemic young adults. Proceedings of the Nutrition Society 70 (OCE4):E245, 2011. |
| 27356528 | Derived | Toxqui L, Vaquero MP. Aldosterone changes after consumption of a sodium-bicarbonated mineral water in humans. A four-way randomized controlled trial. J Physiol Biochem. 2016 Dec;72(4):635-641. doi: 10.1007/s13105-016-0502-8. Epub 2016 Jun 29. |