The aim of the study is to investigate the impact of adjuvant chemotherapy on cognitive function in patients aged over 65 and suffering from breast cancer or colon.

Inclusion Criteria for patients with chemotherapy :

• Patient(e) aged over 65 years
• Non metastatic breast cancer
• Adjuvant chemotherapy Breast cancer: FEC, including Docetaxel Protocols
• No major cognitive impairment
• Lack of personality disorders and psychiatric disorders evolutionary
• Having signed the informed consent of study participation

Inclusion Criteria for patients without chemotherapy (control group):

• Patient(e) aged over 65 years
• Breast cancer
• Patients receiving no adjuvant chemotherapy
• No major cognitive impairment
• Lack of personality disorders and psychiatric disorders evolutionary
• Having signed the informed consent of study participation
• Matching on age, sex, cultural level and tumor location

Exclusion Criteria for patients with chemotherapy :

• Metastatic
• Cancer primitive other than breast
• Patients under 65 years
• Patients with adjuvant chemotherapy is associated with targeted therapy
• Patients who have received other cancer treatments (chemotherapy or radiotherapy brain)
• disorders of higher functions existing in the administration of chemotherapy
• Pathology psychiatric evolutionary
• Refusal of participation
• Patients unable to meet the cognitive tests
• Drug use
• Heavy drinking

patients with chemotherapy group and patients without chemotherapy group (control group)