Inclusion Criteria for patients:
- Patients aged 45 and over
- Patients from Grade 3 'end of primary schooling "minimum (scale Barbizet)
- Non-Metastatic Breast Cancer
- Adjuvant Chemotherapy: FEC, including Docetaxel Protocols
- No major cognitive impairment
- No previous neurological
- Lack of personality disorders and psychiatric disorders evolutionary
- Having signed the informed consent of study participation
Inclusion Criteria for control group:
- Women from the general population aged 45 and over, and matched in age and cultural level in patients
- Topics of Grade 3 'end of primary schooling "minimum (scale Barbizet)
- No prior cancer
- No major cognitive impairment
- No previous neurological
- Lack of personality disorders and psychiatric disorders evolutionary
- Participating in the IMAP Protocol No. ID-BCR: 2007-A00414-49 or IMAP+(n° ID RCB 2011-A01493-38)(see how the study below) have signed forms no objection and consent to study participation
Exclusion Criteria:
Traduction (français > anglais)
- Metastatic
- Cancer of the breast other than primitive
- Patients with paraneoplastic syndrome
- Patients under 45 years
- Patients whose achievement is below level 3 'end of primary schooling "(scale Barbizet)
- Patients with adjuvant chemotherapy is associated with targeted therapy
- Patients who have received other cancer treatments (chemotherapy or radiotherapy brain)
- Contraindication to the implementation of an MRI (claustrophobia, metal objects in the body)
- disorders of higher functions existing in the administration of chemotherapy
- Neurologic earlier
- Pathology psychiatric evolutionary
- Refusal of participation
- Patients unable to meet the cognitive tests
- Drug use
- Heavy drinking